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2010年度

神経機能形態学

1. Hori H, Ozeki Y, Teraishi T, Matsuo J, Kawamoto Y, Kinoshita Y, Suto S, Terada S, Higuchi T, Kunugi H: Relationships between psychological distress, coping styles, and HPA axis reactivity in healthy adults. J Psychiatr Res. 2010 Oct;44(14):865-73.
2. Nagashima Y, Suzuki T, Terada S, Tsuji S, Misawa K. Improved signal extraction method for single-pulse het- erodyne CARS spectroscopy (Proceedings Paper). Proc SPIE, 7376 Laser Applications in Life Sciences, Matti Kinnunen, Risto Myllylä Editors, 73760S, 24 Nov 2010.
3. Nagashima Y, Suzuki T, Terada S, Tsuji S, Misawa K. In vivo molecular labeling of halogenated volatile anesthet- ics via intrinsic molecular vibrations using nonlinear Raman spectroscopy. J. Chem. Phys., 134, 024525 (2011); Published online, 13 January 2011.

細胞生理学

1. Yoshii, S.R., Kishi, C., Ishihara, N., Mizushima, N. Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J. Biol. Chem. in press
2. Asano, T., Komatsu, M., Yamaguchi-Iwai, Y., Ishikawa, F., Mizushima, N., Iwai, K. Distinct mechanisms of fer- ritin delivery to lysosomes in iron depleted and iron- replete cells. Mol. Cell. Biol. in press
3. Takamura, A., Komatsu, M., Hara, T., Sakamoto, A., Kishi, C., Waguri, S., Eishi, Y., Hino, O., Tanaka, K., Mizushima, N. Autophagy-deficient mice develop multi- ple liver tumors. Genes Dev. 25: 795-800 (2011).
4. Itakura, E., Mizushima, N. p62 targeting to the autophagosome formation site requires self-oligomer- ization but not LC3 binding. J. Cell Biol. 192: 17-27 (2011).
5. Riley, B.E., Kaiser, S.E., Shaler, T.A., Ng, A.C., Hara, T., Hipp, M.S., Lage, K., Xavier, R.J., Ryu, K.Y., Taguchi, K., Yamamoto, M., Tanaka, K., Mizushima, N., Komatsu, M., Kopito, R.R. Ubiquitin accumulation in autophagy- deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggrega- tion in autophagic substrate selection. J. Cell Biol. 191: 537-552 (2010).
6. Itakura, E., Mizushima, N. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 6: 764-76 (2010).
7. Taneike, M., Yamaguchi, O., Nakai, A., Hikoso, S., Takeda, T., Mizote, I., Oka, T., Tamai, T., Oyabu, J., Murakawa, T., Nishida, K., Shimizu, T., Hori, M., Komuro, I., Shirasawa, T., Mizushima, N., Otsu, K. Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 6: 600-606 (2010).
8. Kaizuka, T., Hara, T., Oshiro, N., Kikkawa, U., Yonezawa, K., Takehana, K., Iemura, S., Natsume, T., Mizushima, N. Tti1 and Tel2 are critical factors in mam- malian target of rapamycin complex assembly. J. Biol. Chem. 285: 20109-20116 (2010).

病態代謝解析学

1. Fukaya M, Kamata A, Hara Y, Tamaki H, Katsumata O, Ito N, Takeda S, Hata Y, Suzuki T, Watanabe M. Harvey RJ, Sakagami H. SynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapse. J. Neurochem. 116, 1122-1137, 2011.
2. Aguilera C*, Nakagawa K*, Sancho R, Chakraborty A, Hendrich B, Behrens A. c-Jun N-terminal phosphorylati- ton antagonizes recruitment of the Mbd3/NuRD repres- sor complex. Nature 469, 231-235, 2011 (*, The authors contributed equally to the work)
3. Kaufman L, Potla U, Coleman S, Dikiy S, Hata Y, Kurihara H, He JC, D'Agati VD, Klotman PE. Upregulation of the homophilic adhesion molecule Sidekick-1 in podocytes contributes to glomeruloscrelo- sis. J. Biol. Chem. 285, 25677-25685, 2010.
4. Nakagawa K, Sugahara M, Yamasaki T, Kajiho H, Takahashi S, Hirayama J, Minami Y, Ohta Y, Watanabe T, Hata Y, Katada T, Nishina H. Filamin associates with stress signaling kinases MKK7 and MKK4 and regulates JNK activation. Biochem. J. 427, 237-245, 2010.
5. Iwasa H, Yu S, Xue J, Driscoll M. Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation. Aging Cell 9, 490-505, 2010.

分子神経科学

1. Harada, C., Namekata, K., Guo, X., Yoshida, H., Mitamura, Y., Matsumoto, Y., Tanaka, K., Ichijo, H., Harada, T. ASK1 deficiency attenuates neural cell death in a GLAST deficient mice, a model of normal tension glaucoma. Cell Death Differ 17. 1751-1759, 2010.
2. Paukert, M., Huang, Y.H., Tanaka, K., Rothstein, J.D., Bergles, D.E. Zones of enhanced glutamate release from climbing fibers in the mammalian cerebellum. J Neurosci 30. 7290-7299, 2010.
3. Woltjer, RL., Duerson K., Fullmer, JM., Mookherjee, P., Ryan, AM., Montine, TJ., Kaye, JA., Quinn, JF., Silbert, L., Erten-Lyons, D., Leverenz, JB., Bird, TD., Pow, DV., Tanaka, K., Watson, S., Cook, DG. Aberrant detergent- insoluble EAAT2 accumulates in Alzheimer's disease. J Neuropath Exp Neur 69. 667-676, 2010.
4. Swartling, F.J., Grimmer, M., Hackett, C.S., Northcott, P.A., Fan, Q-W., Goldenberg, D.D., Lau, J., Masic, S., Nguyen, K., Yakovenko, S., Zhe, X-N., Glimer, H.C.F., Collins, R., Nagaoka, M., Phillips, J.J., Jenkins, R.B.,
5. Tihan, T., Vandenberg, S.R., James, C.D., Tanaka, K., Taylor, M.D., Weiss, W.A., Chesler, L. Pleiotropic Role for MYCN in medulloblastoma. Genes Dev 24. 1059- 1072, 2010.
Nakamori, T., Sato, K., Atoji, Y., Kanamatsu, T., Tanaka,
K., Ohki-Hamazaki, H. Demonstration of a neural circuit critical for the imprinting behavior in chicks. J Neurosci 30. 4467-4480, 2010.

神経病理学

1. Enokido, Y., Tamura, T., Ito, H., Arumughan, A., Komuro, A., Shiwaku, H., Sone, M., Foulle, R., Sawada, H., Ishiguro, H., Ono, T., Murata, M., Kanazawa, I., Tomilin, N., Tagawa, K., Wanker, E.E., and Okazawa, H. (2010). Mutant huntingtin impairs Ku70-mediated DNA repair. J Cell Biol. 189, 425-443.
2. Takahashi, M., Mizuguchi, M., Shinoda, H., Aizawa, T., Demura, M., Okazawa, H., and Kawano, K. (2010). Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain. Biochim Biophys Acta. 1804, 1500-1507.
3. Shiwaku, H., Yoshimura, N., Tamura, T., Sone, M., Ogishima, S., Watase, K., Tagawa, K., and Okazawa, H.(2010). Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell- autonomous toxicity. EMBO J. 29, 2446-2460.
4. Honda, S., Hayashi, S., Imoto, I., Toyama, J., Okazawa, H., Nakagawa, E., Goto, Y., and Inazawa, J. (2010). Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis. J Hum Genet. 55, 590-599.
5. Konno, M., Hamazaki, T. S., Fukuda, S., Tokuhara, M., Uchiyama, H., Okazawa, H., Okochi, H., and Asashima, M. (2010). Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture. Biochem Biophys Res Commun. 400, 461-465.
6. Tamura, T., Horiuchi, D., Chen, Y. C., Sone, M., Miyashita, T., Saitoe, M., Yoshimura, N., Chiang, A. S., and Okazawa, H. (2010). Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning. J Neurosci. 30, 14091-14101.
7. Aoki, Y., Nakamura, A., Yokota, T., Saito, T., Okazawa, H., Nagata, T., and Takeda, S. (2010). In-frame Dystrophin Following Exon 51-Skipping Improves Muscle Pathology and Function in the Exon 52-Deficient mdx Mouse. Mol Ther. 18, 1995-2005.

神経生理学

1. Fujita H, Oh-Nishi A, Obayashi S, Sugihara I. Projection of reconstructed single Purkinje cell axons in relation to the cortical and nuclear aldolase C compartments of the rat cerebellum. J Comp Neurol 518: 1764-1791, 2010.
2. Takahashi M, Sugiuchi Y and Shinoda, Y. Topographic organization of excitatory and inhibitory commissural connections in the superior colliculi and their functional roles in saccade generation. J. Neurophysiol. 104: 3146- 3167, 2010.
3. Oh-Nishi A, Obayashi S, Sugihara I, Minamimoto T, Suhara T. Maternal immune activation by polyri- boinosinic-polyribocytidilic acid injection produces synaptic dysfunction but not neuronal loss in the hip- pocampus of juvenile rat offspring. Brain Res 1363: 170- 179, 2010.

細胞生物学

1. Ishii T, Mombaerts P. Coordinated coexpression of two vomeronasal receptor V2R genes per neuron in the mouse. Mol Cell Neurosci. 2011 Feb;46(2):397-40.

認知神経生物学

1. Ojima H, Taoka M, Iriki A: Adaptive changes in firing of primary auditory cortical neurons following illumination shift from light to dark in freely moving guinea pigs. Cereb Cortex, 20:339-351, 2010.
2. Katsuyama N, Yamashita A, Sawada K, Naganuma T, Sakata H, Taira M: Functional and histological properties of caudal intraparietal area of macaque monkey., Neuroscience, 167:1-10, 2010.
3. Katsuyama N, Usui N, Nose I, Taira M: Perception of object motion in three-dimensional space induced by cast shadows. Neuroimage, 54:485-494, 2011.
4. Katsuyama N, Imamura K, Onoe H, Tanaka HK, Onoe K, Tsukada H, Watanabe Y: Cortical activation during color
discrimination task in macaques as revealed by positron emission tomography. Neurosci Lett., 484:168-173, 2010.
5. Sato N, Sakata H, Tanaka YL, Taira M: Context-depend- ent place-selective responses of the neurons in the medial parietal region of macaque monkeys, Cereb Cortex, 20:846-858, 2010.
6. Yamashita A, Fuchs E, Taira M, Hayashi M: Amyloid beta (A β) protein- and amyloid precursor protein (APP)- immunoreactive structures in the brains of aged tree shrews, Curr Aging Sci., 3:230-238, 2010.

分子遺伝学

1. Shiwaku, H., Yoshimura, N., Tamura, T., Sone, M., Ogishima, S., Watase, K., Tagawa, K. and Okazawa H. Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. 2010. EMBO J., 29(14): 2446-2460.

分子生物学

1. Itsuki Ajioka, Shizuko Ichinose, Kazunori Nakajima, and Hidehiro Mizusawa “Basement Membrane-like Matrix Sponge for the Three- dimensional Proliferation Culture of Differentiated Retinal Horizontal Interneurons”Biomaterials (in press)

脳神経病態学

1. Hizume M, Kobayashi A, Teruya K, Ohashi H, Ironside JW, Mohri S, Kitamoto T. Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection. J Biol Chem 2009; 284: 3603-3609.
2. Irioka T, Yamanami A, Uchida N, Iwase M, Yasuhara H, Mizusawa H. Opsoclonus caused by diphenhydramine self-poisoning. J Neuro Ophthalmol. 2009; 29: 72-73.
3. Irioka T, Yamanami A, Yagi Y, Mizusawa H. Aortic dissection as a possible cause of pure transient global amnesia: a case report and literature review. Neurol Sci 2009; 30: 255-258.
4. Ishibashi S, Maric D, Mou Y, Ohtani R, Ruetzler C, Hallenbeck JM. Mucosal tolerance to E-selectin promotes the survival of newly generated neuroblasts via regulatory T-cell induction after stroke in spontaneously hypertensive rats. J Cereb Blood Flow Metab 2009; 29: 606-620.
5. Ishiguro T, Ishikawa K, Takahashi M, Obayashi M, Amino T, Sato N, Sakamoto M, Fujigasaki H, Tsuruta F, Dolmetsch R, Arai T, Sasaki H, Nagashima K, Kato T, Yamada M, Takahashi H, Hashizume Y, Mizusawa H. The carboxy-terminal fragment of α1A-calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells. Acta Neuropathol 2009 [Epub]2009.12.31.
6. Kinoshita H, Okabayashi M, Kaneko M, Yasuda M, Abe K, Machida A, Ohkubo T, Kamata T, Yakushiji F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. J Altern Complement Med 2009; 15: 439-443.
7. Kobayashi A, Hizume M, Teruya K, Mohri S, Kitamoto T. Heterozygous inhibition in prion infection: the stone fence model. Prion 2009; 3: 27-30.
8. Kobayashi Z, Tsuchiya K, Uchihara T, Nakamura A, Haga C, Yokota O, Ishizu H, Taki K, Arai T, Akiyama H, Mizusawa H. Intractable hiccup caused by medulla oblongata lesions in a patient with autopsy-proven neuromyelitis optica. J Neurol Sci 2009; 285: 241-245.
9. Kobayashi Z, Tsuchiya K, Machida A, Goto J, Miake H, Watabiki S, Taki K, Haga C, Yokota O, Arai T, Akiyama H, Mizusawa H. Metastatic CNS lymphoma presenting with periventricular dissemination- an autopsy case with an unusual MRI. J Neurol Sci 2009; 277: 109-113.
10. Miki K, Ishibashi S, Sun L, Xu H, Ohashi W, Kuroiwa T, Mizusawa H. Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice. J Neurosci Res 2009; 87: 1270-1281.
11. Nishida Y, Saito Y, Yokota T, Kanda T, Mizusawa H. Skeletal Muscle MRI in Complex Regional Pain Syndrome. Intern Med 2009; 48: 209-212.
12. Nishida Y, Ito S, Ohtsuki S, Yamamoto N, Takahashi T, Iwata N, Jishage K, Yamada H, Sasaguri H, Yokota S, Piao W, Tomimitsu H, Saido TC, Yanagisawa K, Terasaki T, Mizusawa H, Yokota T. Depletion of vitamin E increases amyloid β accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease. J Biol Chem 2009; 284: 33400-33408.
13. Sasaguri H, Mitani T, Anzai M, Kubodera T, Saito Y, Yamada H, Mizusawa H, Yokota T. Silencing efficiency differs among tissues and endogenous microRNA pathway is preserved in short hairpin RNA transgenic mice. FEBS Lett 2009; 583: 213-218.
14. Sato N, Amino T, Kobayashi K, Asakawa S, Ishiguro T, Tsunemi T, Takahashi M, Matsuura T, Flanigan KM, Iwasaki S, Ishino F, Saito Y, Murayama S, Yoshida M, Hashizume Y, Takahashi Y, Tsuji S, Shimizu N, Toda T, Ishikawa K, Mizusawa H. Spinocerebellar ataxia type 31 is associated with “inserted” penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet 2009; 85: 1-14.
15. Sun L, Kuroiwa T, Ishibashi S, Miki K, Li S, Xu H, Endo S, Mizusawa H. Two region-dependent pathways of eosinophilic neuronal death after transient cerebral ischemia. Neuropathology 2009; 29: 45-54.
16. Ota K, Tsunemi T, Saito K, Yamanami F, Watanabe M, Irioka T, Mizusawa H. (18)F-FDG PET successfully detects spinal cord sarcoidosis. J Neurol 2009; 256: 1943-1946.

脳神経機能外科学

1. Fujii M, Nakagawa K, Tomita H, Tone O, Tamaki M, Takada Y, Hokari M, Nariai T, Ohno K: Efficacy of the American Heart Association/American Stroke Association guidelines for ultra-early, intentional antihy- pertensive therapy in intracerebral hemorrhage. J Clin Neurosci. 17;1136-1139, 2010 2010 Jun 9.
2. Hosoda C, Nariai T, Ishiwata K, Shii K, Matsushima Y, Ohno K: Correlation between focal brain metabolism and higher brain function in patients with Moyamoya disease. Int J Stroke 5: 367-373, 2010
3. Inaji M, Sato K, Momose-Sato Y, Ohno K: Voltage-sensi-tive dye imaging analysis of functional development of
the neonatal rat corticostriatal projection. Neuroimage 54: 1831-1839, 2011
4. Ishiwata K, Kimura Y, Oda K, Ishii K, Sakata M,
Kawasaki K, Nariai T, Suzuki Y, Ishibashi K, Mishina M,
Hashimoto M, Ishikawa M, Toyohara J. Development of 63. PET radiopharmaceuticals and their clinical applications
at the Positron Medical Center. Geriatr Gerontol Int.
2010 Jul;10 Suppl 1:S180-96.
5. Karakama J, Nakagawa K, Maehara T, Ohno K: Subarachnoid hemorrhage caused by a ruptured anteri- or spinal artery aneurysm. Neurol Med Chir 50: 1015- 1059, 2010
6. Ohta Y, Nariai T, Kurumaji A, Hirakawa K, Ohno K. Increased binding of inhibitory neuronal receptors in the hippocampus in kainate-treated rats with spontaneous limbic seizures. J Clin Neurosci. 2010 May;17(5):612-6.
7. Tamura K, Aoyagi M, Wakimoto H, Ando N, Nariai T, Yamamoto M, Ohno K: Accumulation of CD133-posi- tive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation. J Neurosurg 2010 Aug; 113(2):310-8.
8. Tanaka Y, Nagaoka T, Nair G, Ohno K, Duong TQ: Arterial spin labeling and dynamic susceptibility contrast CBF MRI in postischemic hyperperfusion, hypercapnia, and after mannitol injection. J Cereb Blood Flow Metab. 2010 Dec 22.
9. Wakamatsu H, Utsuki T, Mitaka C, Ohno K: Clinical sys- tem engineering of long-term automatic thermal control during brain hypothermia under changing conditions. Technol Health Care. 2010 Jan 1;18(3):181-201.
10. Yu I, Inaji M, Maeda J, Okauchi T, Nariai T, Ohno K, Higuchi M, Suhara T: Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography. J Neurotrauma. 2010 Aug;27:1463-75

精神行動医科学

1. Narushima K, McCormick LM, Yamada T, Thatcher RW, Robinson RG. Subgenual cingulate theta activity predicts treatment response of repetitive transcranial magnetic stimulation in participants with vascular depression. J Neuropsychiatry Clin Neurosci. 2010;22:75-84.
2. Hiraoka S, Kajii Y, Kuroda Y, Umino A, Nishikawa T. The development- and phencyclidine- regulated induction of
synapse-associated protein-97 gene in the rat neocor-
tex. Eur Neuropsychopharmacol. 2010;20:176-186.
3. Okamoto N, Nakai T, Sakamoto K, Nagafusa Y, Higuchi T, Nishikawa T: Rapid antidepressant effect of ketamine
anesthesia during electroconvulsive therapy of treat- ment-resistant depression-Open-label trial comparing ketamine and propofol anesthesia-. J ECT. 2010;26:223- 227.
4. Kaji T, Mishima K, Kitamura S, Enomoto M, Nagase Y, Li L, Kaneita Y, Ohida T, Nishikawa T, Uchiyam M. The relationship between late-life depression and life stres- sors: A large-scale cross-sectional study of a representa- tive sample of the japanese general population. Psychiatry and Clinical Neurosciences. 2010;64:426-434.
5. Oshima K, Okimura T, Yukizane T, Yasumi K, Iwawaki A, Nishikawa T, Hanamura S. Reliability and disgnostic validity for schizophrenia of Japanese version of the Bonn Scale for Assessment of Basic Symptoms (BSABS). J Med Dent Sci. 2010;57:83-94.
6. Asukai N, Saito A, Tsuruta N, Kishimoto J, Nishikawa T. Efficacy of exposure therapy for Japanese patients with posttraumatic stress disorder due to mixed traumatic events: A randomized controlled study. J Trauma Stress. 2010;23:744-750.
7. Kuroda Y, Motohashi N, Ito H, Ito S, Takano A, Takahashi H, Nishikawa T, Suhara T. Chronic repetitive transcranial magnetic stimulation failed to change dopamine synthesis rate: Preliminary L-[b-11C]DOPA positron emission tomography study in patients with depression, Psychiatry and Clinical Neurosciences. 2010;64:659-662.
8. Shioiri A, Kurumaji A, Takeuchi T, Matsuda H, Arai H, Nishikawa T, White matter abnormalities as a risk factor for postoperative delirium revealed by diffusion tensor imaging, Am J Geriatr Psychiatry. 2010;18:743-753.
9. Uchida S, Nishida M, Shioda K, Morita Y. Understanding human biological rhythm. Therapeutic principles of bright light and melatonin for sleep disorders of circadi- an rhythm. Indian J Sleep Med. 2010; 5(1): 8-12.
10. Sekine M, Arakawa R, Ito H, Okumura M, Sasaki T, Takahashi H, Takano H, Okubo Y, Halldin C, Suhara T. Norepinephrine transporter occupancy by antidepres- sant in human brain using positron emission tomogra- phy with (S,S)-[18F]FMeNER-D2. Psychopharmacology (Berl). 2010 Jun;210(3):331-336.
11. Gujar N, McDonald S, Nishida M, Walker MP. A role for REM sleep in (re)calibrating the sensitivity of the human brain to specific emotions. Cereb Cortex. 2011;21(1):115- 123.

耳鼻咽喉科学

1. Tsunoda A, Takahashi N, Kitamura K: The relationship between the superior canal dehiscence syndrome and human evolution: Does human evolution cause vertigo? J Vestibul Res-Equil 20: 278, 2010.
2. Suzuki M, Tsunoda A, Shirakura S, Sumi T, Nishijima W, Kishimoto S: A novel permanent tracheostomy tech- nique for prevention of stomal stenosis (triangular tra- cheostomy). Auris Nasus Larynx 37: 465-8, 2010.
3. Abe S, Noguchi Y, Kitamura K: What do patients with hereditary deafness think of genetic studies? Auris Nasus Larynx 37: 422-6, 2010.
4. Yashima T, Noguchi Y, Kawashima Y, Rai T, Ito T, Kitamura K: Novel ATP6V1B1 mutations in distal renal tubular acidosis and hearing loss. Acta Otolaryngol 130: 1002-8, 2010.
5. Shirakura S, Tsunoda A, Akita K, Sumi T, Suzuki M, Sugimoto T, Kishimoto S: Parapharyngeal space tumors: Anatomical and image analysis findings. Auris Nasus Larynx 37: 621-5, 2010.
6. Lelli A, Kazmierczak P, Kawashima Y, Müller U, Holt JR: Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15. J Neurosci 30: 11259-69, 2010.
7. Ariizumi Y, Hatanaka A, Kitamura K: Clinical prognostic factors for tinnitus retraining therapy with a sound gen- erator in tinnitus patients. J Med Dent Sci 57: 45-53, 2010.
8. Ohno K, Noguchi Y, Kawashima Y, Yagishita K, Kitamura K: Secondary hyperbaric oxygen therapy for idiopathic sudden sensorineural hearing loss in the suba- cute and chronic phases. J Med Dent Sci 57: 127-32, 2010.
9. Kato T, Nishigaki Y, Noguchi Y, Ueno H, Hosoya H, Ito T, Kimura Y, Kitamura K, Tanaka M: Extensive and rapid screening for major mitochondrial DNA point mutations in patients with hereditary hearing loss. J Hum Genet. 55: 147-54, 2010.
10. Iwasaki A, Tokano H, Kamiyama R, Suzuki Y, Kitamura K: A 24-month-follow-up study of argon plasma coagu- lation of the inferior turbinate in patients with perennial nasal allergy. J Med Dent Sci 57: 11-5, 2010.
11. Takahashi M, Kimura Y, Sawabe M, Kitamura K: Modified paraffin-embedding method for the human cochlea that reveals a fine morphology and excellent immunostaining results. Acta Otolaryngol 130: 788-92, 2010.
12. Fujikawa T, Noguchi Y, Ito T, Takahashi M, Kitamura K: Additional heterozygous 2507A>C mutation of WFS1 in progressive hearing loss at lower frequencies. Laryngoscope 120: 166-71, 2010.
13. Mochizuki E, Okumura K, Ishikawa M, Yoshimoto S, Yamaguchi J, Seki Y, Wada K, Yokohama M, Ushiki T, Tokano H, Ishii R, Shitara H, Taya C, Kitamura K, Yonekawa H , Kikkawa Y: Phenotypic and expression analysis of a novel spontaneous MYOSIN VI null mutant mouse. Exp Anim 59: 57, 2010.
14. Inaba Y, Tokano H, Ohtsu A, Kitamura K: A case of descending necrotizing mediastinitis penetrating to esophagus. J Rural Medicine 5: 190-3, 2010.

眼科学

1. Emoto H, Suzuki Y, Wakakura M, Horie C, Kiyosawa M, Mochizuki M, Kawasaki K, Oda K, Ishiwata K, Ishii K. Photophobia in essential blepharospasm - A positron emission tomographic study. Mov Disord, 2010; 25: 433-439.
2. Emoto H, Emoto Y, Lim JI, Sadun AA, Sebag J. Regression of choroidal neovascularization after vitrecto- my for postinjection endophthalmitis. Retin Cases Brief Rep, 2010; 4: 312-316.
3. Hashimoto Y, Funamoto S, Sasaki S, Honda T, Hattori S, Nam K, Kimura T, Mochizuki M, Fujisato T, Kobayashi H, Kishida A. Preparation and characterization of decellu- larized cornea using high-hydrostatic pressurization for corneal tissue engineering. Biomaterials, 2010; 31: 3941-8.
4. Hayashi K, Ohno-Matsui K, Shimada N, Moriyama M, Kojima A, Hayashi W, Yasuzumi K, Nagaoka N, Saka N, Yoshida T, Tokoro T, Mochizuki M. Long-term Results of Photodynamic Therapy for Choroidal Neovascularization in Japanese Patients with Pathological Myopia. Am J
Ophthalmol, 2010; 151: 137-147.
5. Hayashi K, Ohno-Matsui K, Shimada N, Moriyama M,
Kojima A, Hayashi W, Yasuzumi K, Nagaoka N, Saka N, Yoshida T, Tokoro T, Mochizuki M. Long-term Pattern of Progression of Myopic Maculopathy A Natural History Study. Ophthalmology, 2010. :117:1595-1611.
6. Horie S, Sugita S, Futagami Y, Yamada Y, Mochizuki M. Human retinal pigment epithelium-induced CD4+CD25+ regulatory T cells suppress activation of intraocular effector T cells. *co-first authors. Clin. Immunol, 2010; 136: 83-95.
7. Ito M, Yokoi T, Sugita S, Shinohara N, Nishina S, Azuma N. Endogenous candida chorioretinitis in a healthy infant. Jpn J Ophthalmol, 2010; 54: 629-31.
8. Kamoi K, Mochizuki M. Phaco forward-chop technique for managing posterior nuclear plate in hard cataract. J Cataract Refractive Surg, 2010; 36: 9-12.
9. Kawaguchi T, Sugita S, Yamada Y, Miyanaga M, Mochizuki M. Regression of optic disc neovasculariza- tion in patients with Behçt's uveoretinitis after infliximab therapy. J Ocul Pharmacol Ther, 2010; 26: 627-630.
10. Miyanaga M, Kawaguchi T, Miyata K, Horie S, Mochizuki M, Herbort CP. Indocyanine green angiogra- phy findings in initial acute pretreatment Vogt- Koyanagi- Harada disease in Japanese patients. Jpn J Ophthalmol, 2010; 54: 377-382.
11. Miyanaga M, Sugita S, Shimizu N, Morio T, Miyata K, Maruyama K, Kinoshita S, Mochizuki M. A significant association of viral loads with corneal endothelial cell damage in cytomegalovirus anterior uveitis. Br J Ophthalmol, 2010; 94: 336-340.
12. Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H. Genome-wide association studies define IL23R/IL12RB2 and IL10 as susceptibility loci for Behçt's disease. Nat Genet, 2010; 42: 703-6.
13. Nakauchi Y, Takase H, Sugita S, Mochizuki M, Shibata S, Ishiwata Y, Shibuya Y, Yasuhara M, Miura O, Arai A. Concurrent administration of intravenous systemic and intravitreal methotrexate for intraocular lymphoma with central nervous system involvement. Int J Hematol, 2010; 92: 179-185.
14. Saka N, Ohno-Matsui K, Shimada N, Sueyoshi S, Nagaoka N, Hayashi W, Hayashi K, Moriyama M, Kojima A, Yasuzumi K, Yoshida T, Tokoro T, Mochizuki M. Long-term changes of axial length in eyes of adults with pathologic myopia. Am J Ophthalmol, 2010; 150: 562- 568.
15. Shimada N, Ohno-Matsui K, Iseki S, Koike M, Uchiyama Y, Wang J., Yoshida T, Sato T, Peters C., Mochizuki M, Morita I. Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization. Am J Pathol, 2010; 176: 2571-2580.
16. Sugita S, Horie S, Yamada Y, Keino H, Usui Y, Takeuchi M, Mochizuki M. Suppression of bystander T helper 1 cells by Iris pigment epithelium-inducing regulatory T cells via negative costimulatory signals. Invest. Ophthalmol. Vis. Sci, 2010;51:2529-2536.
17. Sugita S, Horie S, Yamada Y, Mochizuki M. Inhibition of B cell activation by retinal pigment epithelium. Invest Ophthalmol Vis Sci, 2010; 51: 5783-8.
18. Suzuki Y, Kiyosawa M, Mochizuki M, Ishiwata K, Ishii K.
The pre-supplementary and primary motor areas gener- ate rhythm for voluntary eye opening and closing move- ments. Tohoku J Exp Med, 2010; 222: 97-104.
19. Tanaka A, Takase H, Adamus G, Mochizuki M. Cancer assoiated retinopathy caused by benign tumor. British Journal Ophthalmol, 2010; 94: 514-518.
20. Tanaka A, Ohno-Matsui K, Shimada N, Hayashi K, Shibata Y, Yoshida T, Yamashita M, Tokoro T, Mochizuki M. Prevalence of Strabismus in Patients with Pathologic Myopia. J Med Dent Sci, 2010; 57: 75-82.
21. Yamada Y, Sugita S, Tanaka H, Kamoi K, Kawaguchi T, Mochizuki M. Comparison of infliximab versus ciclosporin during the initial 6-month treatment period in Behçt's disease. Br J Ophthalmol, 2010; 94: 284-8.
22. Yamada Y, Sugita S, Horie S, Yamagami S, Mochizuki M. Mechanisms of immune suppression for CD8+ T cells by human corneal endothelial cells via membrane- bound TGF β. Invest Ophthalmol Vis Sci, 2010; 51: 2548-2557.
23. Yamada Y, Sugita S, Tanaka H, Kamoi K, Takase H, Mochizuki M. Timing of recurrent uveitis in patients with Behçt's disease on infliximab therapy. Br J Ophthalmol, 2010; 95: 205-8.

ペインクリニック

1. Ishikawa S, Ohata M, Ishibashi T, Makita K. Relationship between stroke volume variation and pulse pressure variation during esophagectomy. Anesth Resus 2010; 46: 83-87.
2. Ishikawa S, Shirasawa S, Fujisawa M, Kawano T, Makita K. Compressing the non-dependent lung during one-lung ventilation improves arterial oxygenation, but impairs systemic oxygen delivery by decreasing cardiac output. J Anesth 2010; 24: 17-23.
3. Matsuzawa Y, Nakazawa K, Yamamura A, Akashi T, Kitagaki K, Eishi Y, Makita K. Airway pressure release ventilation reduces the increase in bronchoalveolar lavage fluid HMGB1 levels and lung water in experimental ARDS induced by lung lavage. Eur J Anaesthegiology 2010;27:726-733
4. Nakazawa K, Ohata M, Makita K. Failure of double lumen tube cuff deflation on the cuff leak test. J Cardiothorac Vasc Anesth, 2010;24:1025,
5. Takei T, Nakazawa K, Ishikawa S, Uchida T, Makita K. Cardiac arrest in the left lateral decubitus position and extracorporeal cardiopul- monary resuscitation during neurosurgery: a case report. J Anesth 2010; 24: 447-451.

血管内治療学

1. Shojima M, Nemoto S, Morita A, Miyata T, Namba K, Tanaka Y, Watanabe E. Protected endovascular revas- cularization of subacute and chronic total occlusion of the internal carotid artery. AJNR Am J Neuroradiol. 2010 Mar;31(3):481-6.
2. Shojima M, Nemoto S, Morita A, Oshima M, Watanabe E, Saito N.Role of shear stress in the blister formation of cerebral aneurysms.Neurosurgery. 2010 Nov;67(5):1268-74.
3. Takeuchi S, Takasato Y, Masaoka H, Hayakawa T, Otani N, Yoshino Y, Yatsushige H, Sugawara T. Progressive subdural hematomas after epidural blood patch for spontaneous intracranial hypotension. J Anesth. 2010 Apr;24(2):315-6. Epub 2010 Feb 2.
4. Takeuchi S, Takasato Y, Masaoka H, Hayakawa T, Otani N, Yoshino Y, Yatsushige H, Sugawara T. Middle cere- bral artery occlusion resulting from hypereosinophilic syndrome. J Clin Neurosci. 2010 Mar;17(3):377-8. Epub 2010 Jan 13
5. Takeuchi S, Takasato Y, Masaoka H, Hayakawa T, Otani N, Yoshino Y, Yatsushige H, Sugawara T. Hemorrhagic encephalitis associated with Epstein-Barr virus infection. J Clin Neurosci. 2010 Jan;17(1):153-4. Epub 2009 Dec 9.
6. Yatsushige H, Takasato Y, Masaoka H, Hayakawa T, Otani N, Yoshino Y, Sumiyoshi K, Sugawara T, Miyawaki H, Aoyagi C, Takeuchi S, Suzuki G. Prognosis for severe traumatic brain injury patients treated with bilateral decompressive craniectomy. Acta Neurochir Suppl. 2010;106:265-70.
7. Otani N, Takasato Y, Masaoka H, Hayakawa T, Yoshino Y, Yatsushige H, Miyawaki H, Sumiyoshi K, Sugawara T, Chikashi A, Takeuchi S, Suzuki G. Surgical outcome fol- lowing a decompressive craniectomy for acute epidural hematoma patients presenting with associated massive brain swelling. Acta Neurochir Suppl. 2010;106:261-4.
8. Otani N, Takasato Y, Masaoka H, Hayakawa T, Yoshino Y, Yatsushige H, Miyawaki H, Sumiyoshi K, Sugawara T, Chikashi A, Takeuchi S, Suzuki G. Significance of moni- toring the initial intracranial pressure on hematoma irri- gation with trephination therapy for acute subdural hematomas in critical conditions. Acta Neurochir Suppl. 2010;106:257-60.