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2012年度

神経機能形態学

1. 13C-phenylalanine breath test detects altered phenylalanine kinetics in schizophrenia patients. Teraishi T, Ozeki Y, Hori H, Sasayama D, Chiba S, Yamamoto N, Tanaka H, Iijima Y, Matsuo J, Kawamoto Y, Kinoshita Y, Hattori K, Ota M, Kajiwara M, Terada S, Higuchi T and Kunugi H.Translational Psychiatry 2, e119; doi:10.1038/tp.2012.48 Published online 22 May 2012.
2. Luminescent proteins for high-speed single-cell and whole-body imaging. Saito K, Chang Y-F, Horikawa K, Hatsugai N, Higuchi Y, Hashida M, Yoshida Y, Matsuda T, Arai Y, Nagai T. Nat Commun 3:1262. doi: 10.1038/ncomms2248. 2012.
3. Synchronized ATP oscillations have a critical role in prechondrogenic condensation during chondrogenesis. Kwon HJ, Ohmiya Y, Honma K, Honma S, Nagai T, Saito K, and Yasuda K. Cell Death and Disease 3, e278, 2012.

細胞生理学

1. Saitsu, H., Nishimura, T., Muramatsu, K., Kodera, H., Kumada, S., Sugai, K., Kasai-Yoshida, E., Sawaura, N., Nishida, H., Hoshino, A., Ryujin, F., Yoshioka, S., Nishiyama, K., Kondo, Y., Tsurusaki, Y., Nakashima, M., Miyake, N., Arakawa, H., Kato, M., Mizushima, N., Matsumoto, N. De novo mutations in the autophagy gene encoding WDR45 (WIPI4) cause static encephalopathy of childhood with neurodegeneration in adulthood. Nat. Genet. 45: 445-449 (2013).
2. Nishimura, T., Kaizuka, T., Cadwell, K., Sahani, M.H., Saitoh, T., Akira, S., Virgin, H.W. Mizushima, N. FIP200 regulates targeting of Atg16L1 to the isolation membrane. EMBO Rep. 14: 284-291 (2013).
3. Quy, P.N., Kuma, A., Pierre, P., Mizushima, N. Proteasome-dependent activation of mammalian target of rapamycin complex 1 (mTORC1) is essential for autophagy suppression and muscle remodeling following denervation. J. Biol. Chem. 288: 1125-1134 (2013)
4. Itakura, E., Kishi-Itakura, C., Mizushima, N. The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151: 1256-1269 (2012)

病態代謝解析学

1. Iwasa H, Maimaitia S, Kuroyanagi H, Kawano S, Inami K, Timalsina S, Ikeda M, Nakagawa K, Hata Y. Yes-associated protein homolog, YAP-1, is involved in the thermotolerance and aging in the nematode Caenorhabditis elegans, Exp. Cell Res. 319, 931-945. 2013
2. Iwasa H, Kuroyanagi H, Maimaiti S, Ikeda M, Nakagawa K, Hata Y. Characterization of RSF-1, the Caenorhabditis elegans homolog of the Ras-association domain family protein 1. Exp. Cell Res. 319, 1-11. 2013
3. Kudo T, Ikeda M, Nishikawa M, Yang Z, Ohno K, Nakagawa K, Hata Y. The RASSF3 candidate tumor suppressor induces apoptosis and G1/S cell cycle arrest via p53. Cancer Res. 72, 2901-2911. 2012
4. Nishio M, Hamada K, Kawahara K, Sasaki M, Noguchi F, Chiba S, Mizuno K, Suzuki S, Dong Y, Tokuda M, Morikawa T, Hikasa H, Eggenschwiler J, Yabuta N, Nojima H, Nakagawa K, Hata Y, Nishina H, Mimori K, Mori M, Sasaki T, Mak TW, Nakano T, Itami S, Suzuki A. Cancer susceptibility and embryonic lethality in Mob1A/1B double mutant mice. J. Clin. Invest. 122, 4505-4518. 2012
5. Hata S, Hirayama J, Kajiho H, Nakagawa K, Hata Y, Katada T, Furutani-Seiki M, Nishina H. A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents. J. Biol. Chem. 287, 22089-98, 2012
6. Withanage K, Nakagawa K, Ikeda M, Kurihahara H, Kudo T, Yang Z, Sakanae A, Sasaki T, Hata Y. Expression of RASSF6 in kidney and the implication of RASSF6 and the Hippo pathway in the sorbitol-induced apoptosis in renal proximal tubular epithelial cells. J. Biochem. 152, 111-119. 2012

分子神経科学

1. Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H. Molecular characterization of the subnuclei in rat habenula. J Comp Neurol. 2012, 520:4051-4066.
2. Suzuki, K., Maekawa, F., Suzuki, S., Nakamoi, T., Sugiyama, H., Kanamatsu, T., Tanaka, K., Ohki-Hamazaki, H. Elevated expression of brain-derived neurotrophic factor facilitates visual imprinting in chicks. J Neurochem 123. 800-810, 2012.
3. Hayashi, H., Eguchi, Y., Fukuchi-Nakanishi, Y., Takeya, M., Nakagata, N., Tanaka, K., Vance, JE., Tanihara, H. A potential therapeutic function of apolipoprotein E-containing lipoproteins for normal tension glaucoma. J Biol Chem 287. 25395-25406, 2012.
4. Aida, T., Ito, Y., Takahashi, YK., Tanaka, K. Overstimulation of NMDA Receptors Impairs Early Brain Development in vivo. PlosOne 7.eE36853, 2012.
5. Karlsson, R-M., Adwmark, L., Molander, A., Perreau-Lenz, S., Singley, E., Solomon, M., Holmes, A., Tanaka, K., Lovinger, DM., Spanagel, R., Heiling, M. Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST. Neuropsychopharmacology 63. 181-189, 2012.
6. Tsai, M-C., Tanaka, K., Overstreet-Wadiche, L., Wadiche, JI. Neuronal glutamate transporters regulate glial excitatory transmission. J Neurosci 32. 1528-1535, 2012.
7. Maekawa, F., Sakurai, M., Yamashita, Y., Tanaka, K., Haraguchi, S., Yamamoto, K., Tsutsui, K., Yoshioka, H., Mutakami, S., Maeda, T., Tadano, R., Goto, T., Tomonari, K., Oka, T., Ohara, K., Shiraishi, J., Bungo, T., Tsudzuki, M., Ohki-Hamazki, H. A genetically female brain is required for a regular reproductive cycle in chicken brain chimeras. Nature Commun 4. 1372, 2013.

神経病理学

1. Nakamura, Y., Tagawa, K., Oka, T., Sasabe, T., Ito, H., Shiwaku, H., La Spada, A.R. and Okazawa, H. (2012). Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network. Hum Mol Genet. 21 (5): 1099-1110. doi: 10.1093/hmg/ddr539
2. Ress, M., Gorba, C., Gorba, C., de Chiara, C., Bui, T.T.T., Garcia-Maya, M., Drake, A.F., Okazawa, H., Pastre, A., Svergun, D. and Chen, Y.W. (2012). The solution model of the intrinsically disordered polyglutamine tract binding protein-1 (PQBP-1). Biophys J. 102:1608–1616. doi: 10.1016/j.bpj.2012.02.047
3. Tamura T., Sone M., Nakamura Y., Shimamura T., Imoto S., Miyano S. and Okazawa H. (2012). A restricted level of PQBP1 is needed for the best longevity of Drosophila. Neurobiology of Aging . 2013 Jan;34(1):356.e11-20. doi: 10.1016/j.neurobiolaging.2012.07.015
4. Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, and Okazawa H (2013) A functional deficiency of TERA/VCP/p97 contributes to impaired DNA damage repair in multiple polyglutamine diseases. Nature Commun. In press.

神経生理学

1. Fujita H, Morita N, Furuichi T, Sugihara I (2012) Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration. J. Neurosci. 32: 15688-15703.
2. Brown K, Sugihara I, Shinoda Y, Ascoli G (2012) Digital morphometry of rat cerebellar climbing fibers reveals distinct branch and bouton types. J. Neurosci. 32: 14670-14686.
3. Fujita H, Sugihara I, FoxP2 expression in the cerebellum and inferior olive: development of the transverse stripe-shaped expression pattern in the mouse cerebellar cortex. J Comp Neurol 520: 656-677, 2012.
4. Aoki H, Sugihara I. Morphology of single olivocerebellar axons in the denervation-reinnervation model produced by subtotal lesion of the rat inferior olive. Brain Res 1449: 24-37, 2012.

細胞生物学

1. Ishii, T. Genetic manipulation to analyze pheromone responses: knockouts of multiple receptor genes. Methods Mol. Biol. (in press)

認知神経生物学

1. Yamashita A, Fuchs E, Taira M, Yamamoto T, Hayashi M. Somatostatin-immunoreactive senile plaque-like structures in the frontal cortex and nucleus accumbens of aged tree shrews and Japanese macaques. J Med Primatol 41(3):147-157, 2012.
2. Ojima H, Taira M, Kubota M, Horikawa J. Recognition of non-harmonic natural sounds by small mammals using competitive training. PLos One 7(12): e51318, 2012.

生命機能情報解析学

1. Hara K, Ohta K, Miyajima M, Hara M, Iino H, Matsuda A, Watanabe S, Matsushima E, Maehara T, Matsuura M: Mismatch negativity for speech sounds in temporal lobe epilepsy. Epilepsy Behav 23: 335-341, 2012
2. Sasai T, Inoue Y, Matsuura M: Effectiveness of pramipexole, a dopamine agonist, on rapid eye movement sleep behavior disorder. Tohoku J Exp Med 226: 177-181, 2012
3. Sasai T, Miyamoto M, Iwanami M, Abe T, Matsuura M, Inoue Y:Impaired decision-making in idiopathic REM sleep behavior disorder. Sleep Med 13: 301-306, 2012 .
4. Sasai T, Matsuura M, Wing YK, Inoue Y: Validation of the Japanese version of the REM sleep behavior disorder questionnaire (RBDQ-JP). Sleep Med 13: 913-8, 2012.
5. Sasai T, Inoue Y, Matsuura M: Do patients with rapid eye movement sleep behavior disorder have a disease-specific personality? Parkinsonism Relat Disord 18(5): 616-8, 2012.
6. Takahashi H, Sassa T, Shibuya T, Kato M, Koeda M, Murai T, Matsuura M, Asai K, Suhara T, Okubob Y: Effects of sports participation on psychiatric symptoms and brain activations during sports observation in schizophrenia. Translational Psychiatry 2, e96, doi:10.1038/tp.2012.22 (2012)
7. Ono S, Yoshiura K, Kinoshita A, Kikuchi T, Nakane Y, Kato N, Sadamatsu M, Konishi T, Nagamitsu S, Matsuura M, Yasuda A, Komine M, Kanai K, Inoue T, Osamura T, Saito K, Hirose S, Koide H, Tomita H, Ozawa H, Niikawa N, Kurotaki N: Mutations in PRRT2 responsible for paroxysmal kinesigenic dyskinesias also cause benign familial infantile convulsions. J Hum Genet 57: 338-341, 2012.
8. Hara K, Maehara T, Miyajima M, Ohta K, Iino H, Inaji M, Matsuda A, Matsushima E, Hara M, Matsuura M: Post-operative mismatch negativity recovery in a temporal lobe epilepsy patient with cavernous angioma. Clin Neurol Neurosurg 2012 [Epub ahead of print]
9. Morita A, Kamei S, Sakai T, Ooga K, Matsuura M, Kojima T, Ucjiyama M, Tanaka N, Arakawa Y, Moriyama M: Relationship between quantitative electroencephalogram and interferon-alpha-induced depression in chronic hepatitis C patients. Neuropsychobiol (in press)
10. Sasai T, Matsuura M, Inoue Y: Factors associated with the effect of pramipexole on symptoms of idiopathic REM sleep behavior disorder. Parkinsonism Relat Disord [Epub ahead of print]
11. Koeda M, Takahashi H, Matsuura M, Asai K, Okubo Y: Cerebral responses to vocal attractiveness in schizophrenia: Evidence from fMRI. Frontiers Hum Neurosci (in press)
12. Watanabe S, Hara K, Ohta K, Iino H, Miyajima M, Matsuda A, Hara M, Maehara T, Matsuura M, Matsushima E: Aroma helps to preserve information processing resources of the brain in healthy subjects but not in temporal lobe epilepsy. Seizure (in press)

分子遺伝学

1. Unno, T., Wakamori, M., Koike, M., Uchiyama, Y., Ishikawa, K., Kubota, H., Yoshida, T., Sasakawa, H., Peters, C., Mizusawa, H. and Watase, K. Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6. 2012. Proc. Natl. Acad. Sci. USA., 109(43): 17693-17698, doi:10.1073/pnas.1212786109.

分子生物学

1. Mio Oshikawa, Kei Okada, Kazunori Nakajima, and Itsuki Ajioka: Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner: Development (in press)

脳神経病態学

1. Abe Y, Hashimoto K, Ilinuma K, Ohtsuka Y, Ichiyama T, Kusuhara K, Nomura K, Mizuguchi M, Aiba H, Suzuki Y, Mizusawa H, Hosoya M. Survey of Subacute Sclerosing Panencephalitis in Japan. J Child Neurol. 2012; 27: 1529-1533.
2. Aoki N, Tsuchiya K, Kobayashi Z, Arai T, Togo T, Miyazaki H, Kondo H, Ishizu H, Uchikado H, Katsuse O, Hirayasu Y, Akiyama H. Progressive nonfluent aphasia: A rare clinical subtype of FTLD-TDP in Japan. Neuropathology 2012; 32: 272-279.
3. Hirai T, Enomoto M, Machida A, Yamamoto M, Kuwahara H, Tajiri M, Hirai Y, Sotome S, Mizusawa H, Shinomiya K, Okawa A, Yokota T. Intrathecal shRNA-AAV9 inhibits target protein expression in the spinal cord and dorsal root ganglia of adult mice. Hum Gene Ther Methods 2012; 23: 119-127.
4. Ichijo M, Miki K, Ishibashi S, Tomita T, Kamata T, Fujigasaki H, Mizusawa H. Posterior cerebral artery laterality on MRA predicts long-term functional outcome in middle cerebral artery occlusion. Stroke 2013; 44: 512-515.
5. Ishikawa K. A commentary on confirmation and refinement of an autosomal dominant congenital motor nystagmus locus in chromosome 1q31.3-q32.1. J Hum Genet 57(12):755, 2012. doi: 10.1038/jhg.2012.122. Epub 2012 Nov 15.
6. Kanazawa T, Adachi E, Orimo S, Nakamura A, Mizusawa H, Uchihara T. Pale neurites, premature α-synuclein aggregates with centripetal extension from axon collaterals. Brain Pathol 2012; 1: 67-78.
7. Kanouchi T, Ohkubo T, Yokota T. Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation? J Neurol Neurosurg Psychiatry 2012; 83: 739-745.
8. Kobayashi Z, Arai T, Yokota O, Tsuchiya K, Hosokawa M, Oshima K, Niizato K, Akiyama H, Mizusawa H. Atypical FTLD-FUS associated with ALS-TDP: A case report. Neuropathology 2013; 33: 83-86.
9. Kobayashi M, Ishibashi S, Tomimitsu H, Yokota T, Mizusawa H. Proliferating immature Schwann cells contribute to nerve regeneration after ischemic peripheral nerve injury. J Neuropathol Exp Neurol 2012 ; 71 : 511-519.
10. Kobayashi M, Yokota T, Tomimitsu H, Ishibashi S, Sekiguchi T, Kanouchi T, Ishikawa K, Mizusawa H. Motor-dominant chronic inflammatory demyelinationg polyradiculoneuropathy with Uhthoff-like phenomenon is a distinct clinical entity? Muscle Nerve 2012; 46: 140-142.
11. Kobayashi Z, Akaza M, Numasawa Y, Ishihara S, Tomimitsu H, Nakamichi K, Saijo M, Morio T, Shimizu N, Sanjo N, Shintani S, Mizusawa H. Failure of mefloquine therapy in progressive multifocal leukoencephalopathy: Report of two Japanese patients without human immunodeficiency virus infection. J Neurol Sci 2013; 15: 190-194.
12. Kuwahara H, Matsunaga S. Central pontine myelinolysis associated with pancreatic diabetes. J Neurol 2012; 259: 353-354.
13. Mullah SH, Inaji M, Nariai T, Ishibashi S, Maeda J, Higuchi M, Ohno K. A selective adenosine A2A receptor antagonist SCH58261 ameliorated hyperlocomotion in animal model of lateral fluid percussion brain injury. Acta Neurochurgica Suppl.2013; 118: 88-92.
14. Nakamichi K, Kishida S, Tanaka K, Suganuma A, Sano Y, Sano H, Kanda T, Maeda N, Kira J, Itoh A, Kato N, Tomimoto H, Kurane T, Chang-Kweng Lim, Mizusawa H, Saijo M. Sequential changes in the non-coding control region sequences of JC polyomaviruses from the cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. Arch Virol 2012; 158: 639-650.
15. Nakamichi K, Mizusawa H, Yamada M, Kishida S, Miura Y, Shimokawa T, Takasaki T, Chang-Kweng Lim, Kurane I, Saijo M. Characteristics of progressive multifocal leukoencephalopathy clarified through internet-assisted laboratory surveillance in Japan. BMC Neurology 2012; 12: 121.
16. Nanri K, Niwa H, Mitoma H, Takei A, Ikeda J, Harada T, Okita M, Takeguchi M, Taguchi T, Mizusawa H. Low-Titer Anti-GAD-Antibody-Positive Cerebellar Ataxia. Cerebellum 2012; 12: 171-175.
17. Obayashi M, Ishikawa K, Izumi Y, Takahashi M, Niimi Y, Sato N, Onodera O, Kaji R, Nishizawa M, Mizusawa H. Prevalence of inositol 1, 4, 5-triphosphate receptor type 1 gene deletion, the mutation for spinocerebellar ataxia type 15, in Japan screened by gene dosage. J Hum Genet 2012; 57: 202-206.
18. Ohyagi M, Ohkubo T, Taniyama T, Tomizawa S, Okawa A, Yokota T, Mizusawa H. Spinal Epidural Abscess caused by Bacteroides fragilis group after Dilation and Curettage for Incomplete Abortion. J Glob Infect Dis 2012; 4: 132-134.
19. Ohyagi M, Sanjo N, Yokota T, Mizusawa H. Hereditary Neuropathy with Liability to Pressure Palsy Combined with Suspected Schwannomas of the Peroneal and Radial Nerves. J Neurol 2012; 259: 977-979.
20. Ohyagi M, Ohkubo T, Yagi Y, Ishibashi S, Akiyama J, Nagahori M, Watanabe M, Yokota T, Mizusawa H. Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease. Intern Med 2013; 52: 125-128.
21. Orimo S, Suzuki M, Inaba A, Mizusawa H. I-MIBG myocardial scintigraphy for differentiating Parkinson’s desease from other parkinsonism: A systematic review and meta-analysis. Parkinsonism Related Disord 2012; 18: 494-500.
22. Ozaki A, Nishida M, Koyama K, Ishikawa K, Nishikawa T. Donepezil-induced sleep spindle in a patient with dementia with Lewy bodies: a case report. Psychogeriatrics. 12(4):255-258, 2012. doi: 10.1111/j.1479-8301.2012.00411.x.
23. Soga K, Irioka T, Higashi M, Mizusawa H. Stroke presenting with monoparesis in the lower limb. Intern Med 2012; 51: 819-820.
24. Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, Ogura T, Mizusawa H, Imai T, Miyasaka N, Nanki T. Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity. Arthritis Res Ther. 2012 Mar 6;14(2):R48. [Epub ahead of print]
25. Taira T, Ueta T, Katayama Y, Kimuzuka M, Nemoto A, Mizusawa H, Liu M, Koito M, Hiro Y, Tanabe H. Rate of Complications Among the Recipients of Intrathecal Baclofen Pump in Japan: A Multicenter Study. Neuromodulation 2012; 16: 266-272.
26. Takahashi M, Obayashi M, Ishiguro T, Sato N, Niimi Y, Ozaki K, Mogushi K, Mahmut Y, Tanaka H, Tsuruta F, Dolmetsch R, Yamada M, Takahashi H, Kato T, Mori O, Eishi Y, Mizusawa H, Ishikawa K. Cytoplasmic location of α1A voltage-gated calcium channel C-terminal fragment (Cav2.1-CTF) aggregate is sufficient to cause cell death. PLoS ONE 8(3): e50121, 2013. doi: 10.1371/journal.pone.0050121. Epub 2013 Mar 7.
27. Takahashi M, Ishikawa K, Sato N, Obayashi M, Niimi Y, Ishiguro T, Yamada M, Toyoshima Y, Takahashi H, Kato T, Takao M, Murayama M, Mori O, Eishi Y, Mizusawa H. Reduced brain-derived neurotrophic factor (BDNF) mRNA expression and presence of BDNF-immunoreactive granules in the spinocerebellar ataxia type 6 (SCA6) cerebellum. Neuropathology, Dec;32(6):595-603, 2012. doi: 10.1111/j.1440-1789.2012.01302.x. Epub 2012 Mar 7.
28. Toru S, Kobayashi T, Akaza M, Yokota T, Mizusawa H. Dropped head in polymyositis. Rheumatol Int 2012; 32: 1105-1107.
29. Toru S, Ohara M, Hane Y, Ishiguro T, Kobayashi T. Successful steroid treatment for recurrent Miller Fisher syndrome. Muscle Nerve 2012; 45: 763-764.
30. Unno T, Wakamori M, Koike M, Uchiyama Y, Ishikawa K, Kubota H, Yoshida T, Sasakawa H, Peters C, Mizusawa H, Watase K. Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6. Proc Natl Acad Sci USA. 109(43): 17693-17698, 2012. doi: 10.1073/pnas.1212786109. Epub 2012 Oct 10.
31. Yagi Y, Machida A, Toru S, Kobayashi T, Amano T, Hirokawa K, Kitagawa M. Myotonic dystrophy and lipoma: a new association. Neurol Sci 2012; 33: 1477-1478.
32. Yokote H, Nagasawa M, Ichijo M, Amino T, Fujigasaki H. Autoimmune Polyendocrine Syndrome-3 in a Patient With Late-onset Multiple Sclerosis. Neurologist 2012; 18: 83-84.
33. Yoshioka K, Ishibashi S, Shiraishi A, Yokota T, Mizusawa H. Distal hyperintense vessels on FLAIR images predict large-artery stenosis in patients with transient ischemic attack. Neuroradiology 2013; 55: 165-169.

脳神経機能外科学

1. Hara K, Maehara T, Miyajima M, Ohta K, Iino H, Inaji M, Matsuda A, Matsushima E, Hara M, Matsuura M. Post-operative mismatch negativity recovery in a temporal lobe epilepsy patient with cavernous angioma. Clin Neurol Neurosurg. Epub 2012 Jul 19.
2. Hiura M, Kinoshita N, Izumi S, Nariai T. Comparison of the kinetics of pulmonary oxygen uptake and middle cerebral artery blood flow velocity during cycling exercise. Adv Exp Med Biol. 737:25-31, 2012.
3. Hosoda C, Hanakawa T, Nariai T, Ohno K, Honda M. Neural mechanisms of language switch. J Neurolinguistics. 25:44-61, 2012.
4. Kudo T, Ikeda M, Nishikawa M, Yang Z, Ohno K, Nakagawa K, Hata Y. The RASSF3 candidate tumor suppressor induces apoptosis and G1-S cell-cycle arrest via p53. Cancer Res 72(11):2901-2911, 2012
5. Mori C, Hakuta C, Endo K, Nariai T, Ueno M, Shinada K, Kawaguchi Y. The effects of professional oral health care on patients in the subacute stage of emergent neurosurgical disorders. Spec Care Dentist. 32:259-264, 2012.
6. Mukawa M, Nariai T, Matsushima Y, Tanaka Y, Inaji M, Maehara T, Aoyagi M, Ohno K. Long-term follow-up of surgically treated juvenile patients with moyamoya disease. J Neurosurg Pediatr. 10:451-456, 2012.
7. Mullah SH, Inaji M, Nariai T, Momose-Sato Y, Sato K, Ohno K. Optical analysis of developmental changes in synaptic potentiation in the neonatal rat corticostriatal projection. Neuroscience. 201:338-348, 2012.
8. Sakata M, Oda K, Toyohara J, Ishii K, Nariai T, Ishiwata K. Direct comparison of radiation dosimetry of six PET tracers using human whole-body imaging and murine biodistribution studies. Ann Nucl Med. Epub 2013 Feb 13.
9. Shigeta K, Ohno K, Takasato Y, Masaoka H, Hayakawa T, Yatsushige H, Inaji M, Sumiyoshi K, Momose T, Maeda T: Analysis of DWI ASPECTS and recanalization outcome of patients with acute-phase cerebral infarction. J Med Dent Sci. 59:57-63, 2012
10. Suzuki Y, Nariai T, Kiyosawa M, Mochizuki M, Kimura Y, Oda K, Ishii K, Ishiwata K. Increased Adenosine A1 Receptor Levels in Hemianopia Patients After Cerebral Injury: An Application of PET Using 11C-8-Dicyclopropylmethyl-1-Methyl-3-Propylxanthine. Clin Nucl Med. 37(12):1146-1151, 2012.
11. Takeuchi S, Sugawara T, Masaoka H, Takasato Y. Fourth ventricular meningioma: a case report and literature review. Acta Neurol Belg 112(1):97-100, 2012
12. Tamura K, Wakimoto H, Agarwal AS, Rabkin SD, Bhere D, Martuza RL, Kuroda T, Kasmieh R, Shah K: Multimchanistic tumor targeted oncolytic virus overcomes resistance in Brain tumors. Mol Ther. 21(1):68-77, 2013
13. Yamamoto M, Kawabe T, Higuchi Y, Sato Y, Nariai T, Barfod BE, Kasuya H, Urakawa Y. Delayed complications in patients surviving at least 3 years after stereotactic radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys. 85(1):53-60, 2013.
14. Yano T, Okazaki M, Tanaka K, Iida H, Aoyagi M, Tsunoda A, Kishimoto S. A new concept for classifying skull base defects for reconstructive surgery. J Neurol Surg B Skull Base 73(2):125-131, 2012
15. Yamada M, Tsunoda A, Hagino K, Aoyagi M, Kawano Y, Yano T, Tanaka K, Kishimoto S. Surgical management of large juvenile nasopharyngeal angiofibroma invading the infratemporal fossa with intracranial extradural parasellar involvement in an 8-year-old boy. Auris Nasus Larynx 39(3):341-344, 2012

精神行動医科学

1. Hayashi.H, Naoi.S, Nakagawa. T, Nishikawa. T, Imajoh-Ohmi S, Kondo A, Kubo K, Yabuki T, Hattori A, Hirouchi M, Sugiyama Y. Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates the internalization of MRP4. J Biol Chem, 287:15054-15065, 2012.
2. Ozaki A, Nishida M, Koyama K, Ishikawa K, Nishikawa T. Donepezil-induced sleep spindle in a patient with dementia with Lewy bodies. Psychogeriatrics, 2:255-228,2012.
3. Kurumaji A, Nishikawa T. An anxiogenic drug, FG 7142, induced an increase in mRNA of Btg2 and Adamts1 in the hippocampus of adult mice. Behavioral and Brain Functions. 8:43,2012.
4. Uezato A, Yamamoto N, Kurumaji A, Toriihara A, Umezaki Y, Toyofuku A, Nishikawa T. Improvement of asymmetrical temporal blood flow in refractory oral somatic delusion after successful electroconvulsive therapy. J ECT, 28:50-51,2012. 
5. Uezato A, Kimura-Sato J, Yamamoto N, Iijima Y, Kunugi H, Nishikawa T. Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia. Behavioral and Brain Functions. 8(1):2,2012. 
6. Sasaki T, Ito H, Kimura Y, Arakawa R, Takano H, Seki C, Kodaka F, Fujie S, Takahata K, Nogami T, Suzuki M, Fujiwara H, Takahashi H, Nakao R, Fukumura T, Varrone A, Halldin C, Nishikawa T, Suhara T. Quantification of Dopamine Transporter in Human Brain Using Positron Emission Tomography with 18F-FE-PE2I. J Nucl Med, 53(7): 1065-1073, 2012.
7. Itasaka M, Hanasawa M, Hironaka N, Miyata H, Nakayama K. Facilitation of intracranial self-stimulation behavior in rats by environmental stimuli associated with nicotine. Physiology & Behavior. 107(3): 277-282, 2012.
8. Ishiwata S, Umino A, Umino M, Yorita K, Fukui K, Nishikawa T. Modulation of extracellular D-serine content by calcium permeable AMPA receptors in rat medial prefrontal cortex as revealed by in vivo microdialysis. Internationa Journal of Neuropsychopharmacology. 1-12, 2012.
9. Umezaki Y, Katagiri A, Watanabe M, Takenoshita M. Sakuma T, Sako E, Sato Y. Toriihara A, Uezato A, Shibuya H, Nishikawa T, Motomura H, Toyofuku A. Brain perfusion asymmetries in patients with oral somatic delusions, European Archives of Psychiatry and Clinical Neuroscience, in press, 2013.
10. Ishiwata S, Ogata S, Umino A, Shiraku H, Ohashi Y, Kaji Y, Nishikawa T. Increasing effects of S-methyl-L-cysteine on the extracellular D-serine concentrations in the rat medial frontal cortex. Amino Acids, in press, 2013.

耳鼻咽喉科学

1. Tsunoda A, Sumi T, Shirakura S, Kishimoto S, Aoyagi M, Kawano Y. : Otitis media with effusion and skull base lesion. Skull Base 73: 195, 2012.
2. Tsunoda K, Sasaki T, Tsunoda A, Kobayashi R, Ueha R, Shoji S. : Undiagnosed submucous cleft palate interfering with inhalation therapy and a solution. J Allergy Clin Immunol. Epub 2012 Sep 19.
3. Sumi T, Watanabe I, Tsunoda A, Nishio A, Komatsuzaki A, Kitamura K: Longitudinal study of 29 patients with Meniere’s disease with follow-up of 10 years or more (In commemoration of Professor Emeritus Isamu Watanabe). Acta Otolaryngol 132: 10-15, 2012.
4. Kato T, Nishigaki Y, Noguchi Y, Fuku N, Ito T, Mikami E, Kitamura K and Tanaka M: Extended screening for major mitochondrial DNA point mutations in patients with hereditary hearing loss. J Hum Genet 57: 772-775, 2012.
5. Kato T, Fuku N, Noguchi Y, Murakami H, Miyachi M, Kimura Y, Tanaka M and Kitamura K: Mitochondrial DNA haplogroup associated with hereditary hearing loss in a Japanese population. Acta Otolaryngol 132: 1178-1182, 2012.
6. Takahashi N, Tsunoda A, Shirakura S, Kitamura K: Anatomical feature of the middle cranial fossa in fetal periods: possible etiology of superior canal dehiscence syndrome. Acta Otolaryngol 132: 385-390, 2012.
7. Yamada M, Tsunoda A, Hagino K, Aoyagi M, Kawano Y, Yano T, Tanaka K, Kishimoto S.:  Surgical management of large juvenile nasopharyngeal angiofibroma invading the infratemporal fossa with intracranial extradural parasellar involvement in an 8-year-old boy. Auris Nasus Larynx 39: 341-344, 2012.

眼科学

1. Sugita S, Kamoi K, Ogawa M, Watanabe K, Shimizu N, Mochizuki M. Detection of Candida &Aspergillus species DNA using broad-range real-time PCR for fungal endophthalmitis. Graefes Arch Clin Exp Ophthalmol, 2012; 250: 391-398.
2. Kawazoe Y, Sugita S, Keino H, Yamada Y, Imai A, Horie S, Yamagami S, Mochizuki M. Retinoic acid from retinal pigment epithelium induces T regulatory cells. Exp Eye Res, 2012, 94: 32-40.
3. Shimizu M, Suzuki Y, Kiyosawa M, Wakakura M, Ishii K, Ishiwata K, Mochizuki M. Glucose hypermetabolism in the thalamus of patients with hemifacial spasm. Mov Disord, 2012; 27: 519-525.
4. Akagi-Kurashige Y, Kumagai K, Yamashiro K, Nakanishi H, Nakata I, Miyake M, Tsujikawa A, Moriyama M, Ohno-Matsui K, Mochizuki M, Yamada R, Matsuda F, Yoshimura N. Vascular endothelial growth factor gene polymorphisms and choroidal neovascularization in highly myopic eyes. Invest Ophthalmol Vis Sci, 2012; 53: 2349-2353.
5. Sugita S, Kawazoe Y, Imai A, Yamada Y, Horie S, Mochizuki M. Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behcet's disease. Arthritis Res Ther, 2012; 14: R19
6. Ogawa M, Sugita S, Watanabe K, Shimizu N, Mochizuki M.Novel diagnosis of fungal endophthalmitis by broad-range real-time PCR detection of fungal 28S ribosomal DNA.Graefes Arch Clin Exp Ophthalmol, 2012; 250: 1877-83.
7. Nagata K, Maruyama K, Uno K, Shinomiya K, Yoneda K, Hamuro J, Sugita S, Yoshimura T, Sonoda KH, Mochizuki M, Kinoshita S. Simultaneous analysis of multiple cytokines in the vitreous of patients with sarcoid uveitis. Invest Ophthalmol Vis Sci, 2012; 53: 3827-33.
8. Sugita S, Shimizu N, Watanabe K, Ogawa M, Maruyama K, Usui N, Mochizuki M. Virological analysis in patients with human herpes virus 6 (HHV-6)-associated ocular inflammatory disorders. Invest Ophthalmol Vis Sci, 2012; 53: 4692-4698.
9. Ogawa M, Sugita S, Shimizu N, Watanabe K, Nakagawa I, Mochizuki M. Broad-range real-time PCR assay for detection of bacterial DNA in ocular samples of infectious endophthalmitis. Jpn J Ophthalmol, 2012; 56: 529-535.
10. Kojima K, Maruyama K, Inaba T, Nagata K, Yasuhara T, Yoneda K, Sugita S, Mochizuki M, Kinoshita S. The CD4/CD8 ratio in vitreous fluid Is of high diagnostic value in sarcoidosis. Ophthalmology, 2012; 119: 2386-92.
11. Ohguro N, Sonoda K, Takeuchi M, Matsumura M, Mochizuki M. The 2009 prospective multi-center epidemiologic survey of uveitis in Japan. Jpn J Ophthalmol, 2012; 56: 432-435.
12. Shimizu M, Suzuki Y, Kiyosawa M, Wakakura M, Ishii K, Ishiwata K, Mochizuki M. Glucose hypermetabolism in the thalamus of patients with hemifacial spasm. Mov Disord, 2012; 27: 519-525.
13. Imai A, Sugita S, Kawazoe Y, Horie S, Yamada Y, Keino H, Maruyama K, Mochizuki M. Immunosuppressive properties of regulatory T cells generated by incubation of peripheral blood mononuclear cells with supernatants of human RPE cells. Invest Ophthalmol Vis Sci, 2012; 53: 7299-7309.
14. Ohno-Matsui K, Akiba M, Ishibashi T, Moriyama M. Observations of vascular structures within and posterior to sclera in eyes with pathologic myopia by swept-source optical coherence tomography. Invest Ophthalmol Vis Sci, 2012; 53: 7290-7298.
15. Ohno-MatsuiK, Akiba M, Modegi T, PhD, Tomita M, Ishibashi T, Tokoro T, Moriyama M. Association between shape of sclera and myopic retinochoroidal lesions in patients with pathologic myopia. Invest Ophthalmol Vis Sci, 2012; 53: 6046-6061.
16. Wang J, Ohno-Matsui K, Morita I. Cholesterol enhances amyloid β deposition in mouse retina by modulating the activities of Aβ-regulating enzymes in retinal pigment epithelial cells. Biophys Biochem Res Commun, 2012; 424: 704-709.
17. Moriyama M, Ohno-Matsui K, Modegi T, Kondo J, Takahashi Y, Tomita M, Tokoro T, Morita I. Quatitative analyses of high-resolution 3D MR images of highly myopic eyes to determine their shapes. Invest Ophthalmol Vis Sci, 2012; 53: 4510-4518.
18. Wang J, Ohno-Matsui K, Morita I. Elevated amyloid β production in senescent retinal pigment epithelium, a possible mechanism of age-related subretinal accumulation of amyloid β. Biochem Biophys Res Commun, 2012; 423: 73-78.
19. Verhoeven VJ, Hysi PG, Saw SM, Vitart V, Mirshahi A, Guggenheim JA, Cotch MF, Yamashiro K, Baird PN, Mackey D, Wojciechowski, Ikram MK, Hewitt AW, Duggal P,Janmahasatian S, Khor CC, Fan Q, Zhou X, Young TL, Tai ES ,Goh LK, Li YJ, Aung T, Vithana E, Teo YY, Tay W, Sim X, Rudan I, Hayward C, Wright AF, Polasek O, Campbell H, Wilson JF, Fleck BW, Nakata I, Yoshimura N, Yamada R, Matsuda F, Ohno-Matsui K, Nag A, McMahon G, Pourcain BS, Lu Y, Rahi JS, Cumberland PM, Bhattacharya S, Simpson CL, Atwood LD, Li X, Raffel L, Murgia F, Portas L, Despriet DD, van Koolwijk LM, Wolfram C, Lackner K, Tonjes A, Magi R, Lehtimaki T, Kahonen M, Esko T, Metspalu A, Rantanen T, Parssinen O, BE, Meitinger T, Spector TD, Oostra BA, Smith AV, de Jong PT, Hofman A, Amin N, Karssen LC, Rivadeneira F, Vingerling JR, Eiriksdottir G, Gudnason V, Doring A, Bettecken T, Uitterlinden AG, Williams C, Zeller T, Castagne R, Oexle K, van Duijn CM, Iyengar SK, Mitchell P, Wang JJ, Hohn R, Pfeiffer N, Bailey-Wilson JE, Stambolian D, Wong TY, Hammond CJ, Klaver CC. Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Human Genet, 2012; 131: 1467-1480.
20. Fan Q, Barathi VA, Cheng CY, Zhou X, Meguro A, Nakata I, Khor CC, Goh LK, Li YJ, Lim W, Ho CEH, Hawthorne F, Zheng Y, Chua D, Inoko H, Yamashiro K, Ohno-Matsui K, Matsuo K, Matsuda F, Vithana E, Seielstad1 M, Mizuki N, Beuerman RW, Tai1 ES, Yoshimura N, Aung T, Young TL, Wong TY, Teo YY, Saw SM. Genetic variants on chromosome 1q41 influence ocular axial 1 length and high myopia. PLOS Genetics, 2012; 8: e1002753.
21. Shimada N, Sugamoto Y, Ogawa M, Takase H, Ohno-Matsui K. Fovea-sparing internal limiting membrane peeling for myopic traction maculopathy. Am J Ophthalmol, 2012; 154: 693-701.
22. Asakuma T, Yasuda M, Ohno-Matsui K, Ishibashi T. Prevalence and risk factors for myopic retinopathy in a Japanese population: the Hisayama Study. Ophthalmology, 2012; 119: 1760-1765.
23. Spaide RF, Akiba M, Ohno-Matsui K. Evaluation of peripapillary intrachoroidal cavitation with sept source and enhanced depth imaging optical coherence tomography. RETINA, 2012; 32: 1037-1044.
24. Akagi-Kurashige Y, Kumagai K, Yamashiro K, Nakanishi H, Nakata I, Miyake M, Tsujikawa A, Moriyama M, Ohno-Matsui K, Mochizuki M, Yamada R, Matsuda F, Yoshimura N. Vascular endothelial growth factor gene polymorphisms and choroidal neovascularization in highly myopic eyes. Invest Ophthalmol Vis Sci, 2012; 53: 2349-2353.
25. Ohno-Matsui K, Akiba M, Moriyama M, Ishibashi T, Hirakata A, Tokoro T. Intrachoroidal cavitation in macular area of eyes with pathologic myopia. Am J Ophthalmol, 2012; 154: 382-393.
26. Ohno-Matsui K, Akiba M, Moriyama M, Shimada N, Ishibashi T, Tokoro T, Spaide RF. Acquired optic nerve and peripapillary pits in pathologic myopia. Ophthalmology, 2012; 119: 1685-1692.
27. Tsuchiya K, Moriyama M, Ohno-Matsui K. Development of peripapillary venous loop in eye with small optic disc. Int Ophthalmol, 2012; 32: 171-175.
28. Hayashi K, Shimada N, Moriyama M, Hayashi W, Tokoro T, Ohno-Matsui K. Two year outcomes of intravitreal bevacizumab for choroidal neovascularization in Japanese patients with pathological myopia. RETINA, 2012; 32: 687-695.
29. Kawazoe Y, Sugita S, Yamada Y, Akino A, Miura K, Mochizuki M. Psoriasis triggered by infliximab in a patient with Behçet’s disease, Jpn J Ophthalmol. 2012, (in press) [Epub ahead of print]
30. Ohno-Matsui K, Kasahara K, Moriyama M. Detection of Zinn-Haller arterial ring in highly myopic eyes by simultaneous indocyanine green angiography and optical coherence tomography. Am J Ophthalmol, (in press)
31. Yokoi T, Moriyama M, Hayashi K, Shimada N, Ohno-Matsui K. Evaluation of refractive error after cataract surgery in highly myopic eyes. Int Ophthalmol, (in press)
32. Hayashi K, Katori N, Kasai K, Kamisasanuki T, Kokubo K, Ohno-Matsui K. Comparisons of nylon monofilament suture to polytetrafluoroethylene sheet for frontalis suspension surgery in eyes with congenital ptosis, Am J Ophthalmol (in press)
33. Ishida T, Ohno-Matsui K, Mochizuki M. Polypoidal choroidal vasculopathy in a case with retinitis pigmentosa. Int Ophthalmol, (in press)
34. Miyake M, Yamashiro K, Nakanishi H, Nakata I, Akagi-Kurashige Y, Tsujikawa A, Moriyama M, Ohno-Matsui K, Mochizuki M, Yamada R, Matsuda F, Yoshimura N. Association of paired Box 6 with high myopia in Japanese. Mol Vis, (in press)
35. Saka N, Moriyama M, Shimada N, Nagaoka N, Fukuda K, Hayashi K, Yoshida T, Tokoro T, Ohno-Matsui K. Changes of axial length measured by IOL master during two years in eyes of adults with pathologic myopia. Graefes Arch Clin Exp Ophthalmol, (in press)

ペインクリニック

1. Ishikawa S, Griesdale DEG, Lohser J. Acute kidney injury after lung resection surgery: incidence and perioperative risk factors. Anesth Analg 2012; 114: 1256-62.
2. Ishikawa S. Alveolar recruitment maneuver as an important part of protective one-lung ventilation. J Anesth 2012; 26: 794-5.
3. Nakazawa K, Yokoyama K, Makita K. Cardiac arrest due to pulmonary thromboembolism following administration of spinal anesthesia – a case with femoral neck fracture who was successfully resuscitated with thrombolytic treatment. Anesthesia & Resuscitation 2012;48:71-2,
4. Otsubo Y, Satoh Y, Kodama M, Araki Y, Satomoto M, Sakamoto E, Pagès G, Pouysségur J, Endo S, Kazama T. Mechanical allodynia but not thermal hyperalgesia is impaired in mice deficient for ERK2 in the central nervous system. Pain. 2012;153:2241-52.
5. Yamauchi-Satomoto M, Adachi YU, Kurita T, Morita K, Sato S. Cross-clamping of the descending thoracic aorta leads to the asymmetrical distribution of propofol during cardiopulmonary bypass surgery. Korean J Anesthesiol. 2012;62:327-31.

血管内治療学

1. Namba K, Shojima M, Nemoto S.: Wire-probing technique to revascularize subacute or chronic internal carotid artery occlusion.  Interv Neuroradiol. 18(3):288-96, 2012.
2. Shinya Miyamoto, Henry Wu, Takeshi Kubo, Kenji Kawaguchi, Takafumi Ide, Nobuhiko Takemura, and Shigeru Nemoto: Single stage multiple stenting in Takayasu's arteritis -case report- Neurologia medico-chirurgica 52(4):219-223, 2012
3. Okada T, Teranishi K, Chen Y, Tomori T, Strasser A, Lenz FA, McCarron RM, Spatz M.Reversal of postischemic hypoperfusion by tempol: endothelial signal transduction mechanism Neurochem Res. 2012 Apr;37(4):680-8.
4. Ichijo M, Miki K, Ishibashi S, Tomita M, Kamata T, Fujigasaki H, Mizusawa H. Posterior cerebral artery laterality on magnetic resonance angiography predicts long-term functional outcome in middle cerebral artery occlusion. Stroke. Epub 2012 Nov 27.
5. Takaaki Miyagishima1, Tetsuo Hara, Masato Inoue, Naruhiko Terano1, Hiroyasu Ohno, Kouichiro Okamoto, Kanehiro Hasuo: Pontine venous congestion due to dural arteriovenous fistula of the cavernous sinus: Case report and review of the literature.Surgical Neurology International 2012, 3:53

心療・緩和医療学

1. Takeuchi A, Matsushima E, Kato M, Konishi M, Izumiyama H, Murata Y, Hirata Y. Characteristics of neuropsychological functions in inpatients with poorly-controlled type 2 diabetes mellitus. J Diabetes Invest. 3(3): 325-330, 2012.
2. Suzuki M, Takahashi S, Matsushima E, Tsunoda M, Kurachi M, Okada T, Hayashi T, Ishii Y, Morita K, Maeda H, Katayama S, Otsuka T, Hirayasu Y, Sekine M, Okubo Y, Motoshita M, Ohta K, Uchiyama M, Kojima T: Relationships between exploratory eye movement dysfunction and clinical symptoms in schizophrenia. Pstchiat Clin Neurosci. 66(3): 187-194, 2012.
3. Matsuda A, Hara K, Miyajima M, Matsushima E, Ohta K, Matsuura M. Distinct pre-attentive responses to non-scale notes: An auditory mismatchnegativity (MMN) study. Clin Neurophysiol. 124(6):1115-21, 2013.
4. Watanabe S, Hara K, Ohta K, Iino H, Miyajima M, Matsuda A, Hara M, Maehara T, Matsuura M, Matsushima E. Aroma helps to preserve information processing resources of the brain in healthy subjects but not in temporal lobe epilepsy. Seizure. 22(1):59-63, 2013.
5. Hara K, Ohta K, Miyajima M, Hara M, Iino H, Matsuda A, Watanabe S, Matsushima E, Maehara T, Matsuura M. Mismatch negativity for speech sounds in temporal lobe epilepsy. Epilepsy Behav. 23(3):335-41, 2012.
6. Hara K, Maehara T, Miyajima M, Ohta K, Iino H, Inaji M, Matsuda A, Matsushima E, Hara M, Matsuura M. Post-operative mismatch negativity recovery in a temporal lobe epilepsy patient with cavernous angioma. Clin Neurol Neurosurg. 115(6):756-9, 2012.
7. Noda T, Yoshida S, Matsuda T, Okamoto N, Sakamoto K, Koseki S, Numachi Y, Matsushima E, Kunugi H, Higuchi T. Frontal and right temporal activations correlate negatively with depression severity during verbal fluency task: A multi-channel near-infrared spectroscopy study. Journal of Psychiatric Research. 46: 905-912, 2012.