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2014年度

原著

Nabeshima Y, Mizuguchi M, Kajiyama A, Okazawa H. Segmental isotope-labeling of the intrinsically disordered protein PQBP1. FEBS Lett. 2014 Nov 4. pii: S0014-5793(14)00775-3. doi: 10.1016/j.febslet.2014.10.028. [Epub ahead of print]

Tagawa K, Homma H, Saito A, Fujita K, Chen X, Imoto S, Oka T, Ito H, Motoki K, Yoshida C, Hatsuta H, Murayama S, Iwatsubo T, Miyano S, Okazawa H. Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain. Hum Mol Genet. 2014 Sep 17. pii: ddu475. [Epub ahead of print]

Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Fujita K, Musante L, Fischer U, Frints SG, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Muramatsu SI, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker EE, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer VM, Okazawa H. In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2014 Jul 29. doi: 10.1038/mp.2014.69. [Epub ahead of print]

Ajioka I, Jinnou H, Okada K, Sawada M, Saitoh S, Sawamoto K. Enhancement of Neuroblast Migration into the Injured Cerebral Cortex using Laminin-containing Porous Sponge. Tissue Eng Part A. 2014 Jul 10. [Epub ahead of print]

Mizuguchi M, Obita T, Serita T, Kojima R, Nabeshima Y, Okazawa H. Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15 kD. Nat Commun. 2014 Apr 30;5:3822. doi: 10.1038/ncomms4822


著書・総説

Watase K. Spinocerebellar ataxia type 6: Lessons from faithful knock-in mouse models. Neurology and Clinical Neuroscience. 2014 NOV28, DOI: 10.1111/ncn3.137

味岡逸樹. 神経前駆細胞において増殖と分化の協調を制御するRbファミリータンパク質の役割. 生化学:86, 489-492 (2014)

Ajioka I.Coordination of proliferation and neuronal differentiation by the retinoblastoma protein family.Dev Growth Differ. 2014 Jun;56(5):324-34. doi: 10.1111/dgd.12127.

渡瀬 啓, 水澤英洋. Spinocerebellar ataxia type 6 (SCA6). 2014. 別冊日本臨床 新領域別症候群シリーズ 神経症候群(第2版)II: 350-354.

病態代謝解析学分野

原著
Yang Z, Nakagawa K, Sarkar A, Maruyama J, Iwasa H, Bao Y, Ishigami-Yuasa M, Ito S, Kagechika H, Hata S, Nishina H, Abe S, Kitagawa M, Hata Y. Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in the muscle injury model. Mol.Cell. Biol. 34(9), 1607-1621. 2014. doi: 10.1128/MCB.01346-13. 2014

総説・著書
Kodaka M, Hata Y. The mammalian Hippo pathway: regulation and function of YAP1 and TAZ. Cell Mol Life Sci. 72(2), 285-306. 2015. doi: 10.1007/s00018-014-1742-9. 2015

畑 裕 「広がるHippo pathway研究―癌から各種疾患へ」 企画・編集 医学のあゆみ 第一土曜特集 2014年11月1日

分子神経科学分野

原著
Yanagisawa M, Aida T, Takeda T, Namekata K, Harada T, Shinagawa R, Tanaka K. Arundic acid attenuates retinal ganglion cell death by increasing glutamate/aspartate transporter (GLAST) expression neural cell death in a model of normal tension glaucoma. Cell Death Dis. 2015 Mar 19;6:e1693. doi: 10.1038/cddis.2015.45.

Aida T, Yoshida J, Nomura M, Tanimura A, Iino Y, Soma M, Bai N, Ito Y, Cui W, Aizawa H, Yanagisawa M, Nagai T, Takata N, Tanaka KF, Takayanagi R, Kano M, Götz M, Hirase H, Tanaka K. Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice. Neuropsychopharmacology 2015 Feb 9. doi: 10.1038/npp.2015.26.

Kimura A, Guo X, Noro T, Harada C, Tanaka K, Namekata K, Harada T. Valproic acid prevents retinal degeneration in a murine model of normal tension glaucoma. Neurosci Lett. 588:108-13. doi: 10.1016/j.neulet.2014.12.054.

Nakamori T, Sato K, Kinoshita M, Kanamatsu T, Sakagami H, Tanaka K, Ohki-Hamazaki H. Positive feedback of NR2B-containing NMDA receptor activity is the initial step toward visual imprinting: a model for juvenile learning. J Neurochem.132(1):110-23. doi: 10.1111/jnc.12954.

Cui W, Mizukami H, Yanagisawa M, Aida T, Nomura M, Isomura Y, Takayanagi R, Ozawa K, Tanaka K, Aizawa H. Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance. J Neurosci. 2014 Dec 3;34(49):16273-85. doi: 10.1523/JNEUROSCI.1465-14.2014.

総説・著書
Aida T. Genome editing in mice using TALENs. Targeted Genome Editing Using Site-Specific Nucleases Chapter 11, 167-182, 2015 (Springer).

相澤秀紀、崔万鵬、田中光一 恐怖と不安:脅威に対する動物の適応行動選択とその克服 生体の科学 66(1) 29-32 2015年

システム神経生理学分野

原著
Fujita H, Aoki H, Ajioka I, Yamazaki M, Abe M, Oh-Nishi A, Sakimura K, Sugihara I. Detailed expression pattern of aldolase C (Aldoc) in the cerebellum, retina and other areas of the CNS studied in Aldoc-Venus knock-in mice. PLoS ONE. 2014; 9(1); e86679. doi: 10.1371/journal.pone.0086679. eCollection 2014.

Takahashi M, Sugiuchi Y and Shinoda Y. Convergent synaptic inputs from the caudal fastigial nucleus and the superior colliculus onto pontine and pontomedullary reticulospinal neurons. J. Neurophysiol. 2014; 111; 849-867. doi: 10.1152/jn.00634.2013.

Lang EJ, Tang T, Suh CY, Xiao J, Kotsurovskyy Y, Blenkinsop TA, Marshall SP, Sugihara I. Modulation of Purkinje cell complex spike waveform by synchrony levels in the olivocerebellar system. Front Syst Neurosci. 2014 Oct 30;8:210. doi: 10.3389/fnsys.2014.00210. eCollection 2014.

Xiao J, Cerminara NL, Kotsurovskyy Y, Aoki H, Burroughs A, Wise AK, Luo Y, Marshall SP, Sugihara I, Apps R, Lang EJ. Systematic regional variations in Purkinje cell spiking patterns. PLoS ONE. 2014; 9(8); e105633. doi: 10.1371/journal. pone.0105633. eCollection 2014.

Luo Y, Sugihara I. Cerebellar afferents originating from the medullary reticular formation that are different from mossy, climbing or monoaminergic fibers in the rat. Brain Res. 2014 May 30;1566:31-46. doi: 10.1016/j.brainres.2014.04.020. Epub 2014 Apr 18.

Izawa Y, Suzuki H. Activity of fixation neurons in the monkey frontal eye field during smooth pursuit eye movements. J. Neurophysiol. 2014.07; 112(2); 249-262. doi: 10.1152/jn.00816.2013.

Hamodeh S, Baizer J, Sugihara I, Sultan F. Systematic analysis of neuronal wiring of the rodent deep cerebellar nuclei reveals differences reflecting adaptations at the neuronal circuit and internuclear levels. J. Comp. Neurol. 2014.08; 522(11); 2481-2497. doi: 10.1002/cne.23545.

神経機能形態学分野

原著
Sato K, Roboti P, Mironov AA, Lowe M. Coupling of vesicle tethering and Rab binding is required for in vivo functionality of the golgin GMAP-210. Mol Biol Cell. 2015 Feb 1;26(3):537-53. doi: 10.1091/mbc.E14-10-1450.

Nagai T, Horikawa K, Saito K, Matsuda T. Genetically encoded Ca(2+) indicators; expanded affinity range, color hue and compatibility with optogenetics. Front Mol Neurosci. Nov 25 2014;7:90. doi: 10.3389/fnmol.2014.00090.

総説・著書
小林 靖,寺田純雄. 神経解剖学の見方,考え方, 脳溝の比較解剖と個体発生(2)Clinical Neuroscience. 2015.3; 33(3); 240-241.

小林 靖,寺田純雄. 神経解剖学の見方,考え方, 脳溝の比較解剖と個体発生(1)Clinical Neuroscience. 2015.2; 33(2);124-125.

寺田純雄,小林 靖.神経解剖学の見方、考え方,大脳半球脳表,第三脳室周辺の観察(2)Clinical Neuroscience. 2015.1; 33(1); 4-7.

寺田純雄, 小林靖. 神経解剖学の見方、考え方 大脳半球脳表、第三脳室周辺の観察(1)Clinical Neuroscience. 2014.12; 32(12); 1324-1327.

寺田純雄, 小林靖.神経解剖学の見方、考え方 小脳の解剖(2) Clinical Neuroscience. 2014.11; 32(11);1204-1205.

寺田純雄, 小林靖. 神経解剖学の見方、考え方 小脳の解剖(1) Clinical Neuroscience. 2014.10; 32(10);1076-1079.

小林靖, 寺田純雄. 神経解剖学の見方、考え方 橋小脳とその入出力 Clinical Neuroscience. 2014.09; 32(9);964-965.

寺田純雄, 小林靖. 神経解剖学の見方、考え方 脊髄小脳とその入出力 Clinical Neuroscience. 2014.08;32(8); 844-845.

小林靖, 寺田純雄. 神経解剖学の見方、考え方 前庭小脳とその入出力 Clinical Neuroscience. 2014.07;32(7); 716-717.

寺田純雄, 小林靖. 神経解剖学の見方、考え方 オリーブ核と登上線維(2) Clinical Neuroscience. 2014.06;32(6); 600-601.

寺田純雄, 小林靖. 神経解剖学の見方、考え方 オリーブ核と登上線維(1) Clinical Neuroscience. 2014.05;32(5); 472-473.

小林靖, 寺田純雄. 神経解剖学の見方、考え方 小脳の発生 Clinical Neuroscience. 2014.04; 32(4); 352-353.

佐藤 啓介,寺田 純雄. MAP2 脳科学辞典. 2014.04;DOI:10.14931/bsd.4347

佐藤 啓介,寺田 純雄. 微小管 脳科学辞典. 2014.04;DOI:10.14931/bsd.4389

齊藤健太、永井健治 高輝度化学発光タンパク質Nano-lanternの開発 化学と生物. 2014.52; 646-650

細胞生物学分野

Leinders-Zufall T, Ishii T, Chamero P, Hendrix P, Oboti L, Schmid A, Kircher S, Pyrski M, Akiyoshi S, Khan M, Vaes E, Zufall F, Mombaerts P. A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014 Apr 9;34(15):5121-33. doi: 10.1523/JNEUROSCI.0186-14.2014.

脳神経病態学分野

原著

Asakura T, Ikeda M, Nakamura A, Kodera S. Efficacy of empirical therapy with non-carbapenems for urinary tract infections with extended-spectrum beta-lactamase-producing Enterobacteriaceae. Int J Infect Dis 2014; 29: 91-95.

Furukawa F, Ishibashi S, Sanjo N, Yamashita H, Mizusawa H. Serial magnetic resonance imaging changes in sporadic Creutzfeldt-Jakob disease with valine homozygosity at codon 129 of the prion protein gene. JAMA Neurology 2014; 71(9): 1186-1187.

Furukawa F, Mizusawa H. Central nervous system infection presenting with cognitive impairment. Nihon Rinsho 2014; 72(4): 734-737.

Hattori T, Orimo S, Hallett M, Wu T, Inaba A, Azuma R, Mizusawa H. Relationship and factor structure in multisystem neurodegeneration in Parkinson's disease. Acta Neurol Scand 2014; 130: 347-353.

Hirai T, Enomoto M, Kaburagi H, Sotome S, Yoshida-Tanaka K, Ukegawa M, Kuwahara H, Yamamoto M, Tajiri M, Miyata H, Hirai Y, Tominaga M, Shinomiya K, Mizusawa H, Okawa A, Yokota T. Intrathecal AAV serotype 9-mediated delivery of shRNA against TRPV1 attenuates thermal hyperalgesia in a mouse model of peripheral nerve injury. Mol Ther 2014; 22(2): 409-419.

Ichijo M, Ishibashi S, Ohkubo T, Nomura S, Sanjo N, Yokota T, Mizusawa H. Elevated platelet microparticle levels after acute ischemic stroke with concurrent idiopathic thrombocytopenic purpura. Journal of Stroke and Cerebrovascular Diseases 2014; 23: 587-589.

Ishibashi K, Miura Y, Oda K, Ishiwata K, Ishii K. Alzheimer's disease-like pattern of 18F-FDG uptake during a hyperglycemic state and negative 11C-PiB binding in a patient with mild cognitive impairment. J Alzheimers Dis 2014; 42(2): 385-389.

Ishibashi K, Ishiwata K, Toyohara J, Murayama S, Ishii K. Regional analysis of striatal and cortical amyloid deposition in patients with Alzheimer's disease. Eur J Neurosci 2014; 40(4): 2701-2706.

Ishibashi K, Oda K, Ishiwata K, Ishii K. Comparison of dopamine transporter decline in a patient with Parkinson's disease and normal aging effect. J Neurol Sci 2014; 339(1-2): 207-209.

Iwasa K, Shima K, Komai K, Nishida Y, Yokota T, Yamada M. Retinitis pigmentosa and macular degeneration in a patient with ataxia with isolated vitamin E deficiency with a novel c.717 del C mutation in the TTPA gene. J Neurol Sci 2014; 345(1-2): 228-230.

Kobayashi Z, Watanabe M, Karibe Y, Nakazawa C, Numasawa Y, Tomimitsu H, Shintani S. Right hand predominant constructional apraxia due to right hemisphere infarction without corpus callosum lesions. Intern Med 2014; 53:1553-1558.

Kobayashi Z, Iizuka M, Tomimitsu H, Shintani S. Isolated medial longitudinal fasciculus syndrome due to small midbrain infarction. Neurol Clin Neurosci 2014; 2: 112–113.

Kuwahara H, Tsuchiya K, Kobayashi Z, Inaba A, Akiyama H, Mizusawa H. Cryptococcal meningitis accompanying lymphocytic inflammation predominantly in cerebral deep white matter: A possible manifestation of immune reconstitution inflammatory syndrome. Neuropathology 2014; 34: 45-48.

Mizuno Y, Sakurai Y, Sugimoto I, Ichinose K, Ishihara S, Sanjo N, Mizusawa H, Mannen T. Delayed leukoencephalopathy after carbon monoxide poisoning presenting as subacute dementia. Internal Medicine 2014; 53(13): 1441-1445.

Mizusawa H, Oguchi T, Domen T, Koizumi K, Miura Y, Saito T, Kato H. Two cases of lower abdominal tumors difficult to differentiate from urachal tumors. Nihon Hinyokika Gakkai Zasshi 2014; 105(1): 17-21.

Nanri K, Mitoma H, Ihara M, Tanaka N, Taguchi T, Takeguchi M, Ishiko T, Mizusawa H. Gluten ataxia in Japan. Cerebellum 2014; 13(5): 623-627.

Nishida Y, Ueda A, Ando Y, Ichikawa T. Skin biopsy-based diagnosis of CADASIL with atypical MRI findings. Intern Med 2015;54(5):537-8.

Nishina T, Numata J, Nishina K, Yoshida-Tanaka K, Nitta K, Piao W, Iwata R, Ito S, Kuwahara H, Wada T, Mizusawa H, Yokota T. Chimeric Antisense Oligonucleotide Conjugated to α-Tocopherol. Mol Ther Nucleic Acids 2015 Jan 13;4:e220. doi: 10.1038/mtna.2014.72.

Ota K, Obayashi M, Ozaki K, Ichinose S, Kakita A, Tada M, Takahashi H, Ando N, Eishi Y, Mizusawa H, Ishikawa K. Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy. Acta Neuropathol Commun 2014; 11:136.

Qina T, Sanjo N, Hizume M, Higuma M, Tomita M, Atarashi R, Satoh K, Nozaki I, Hamaguchi T, Nakamura Y, Kobayashi A, Kitamoto T, Murayama S, Murai H, Yamada M, Mizusawa H. Clinical features of genetic Creutzfeldt-Jakob disease with V180I mutation in the prion protein gene. BMJ Open 2014; 4(5): e004968.

Sakakibara S, Aiba I, Saito Y, Inukai A, Ishikawa K, Mizusawa H. Clinical features and MRI findings in spinocerebellar ataxia type 31 (SCA31) comparing with spinocerebellar ataxia type 6 (SCA6). Rinsho Shinkeigaku 2014; 54(6): 473-479.

Sekiguchi T, Kanouchi T, Shibuya K, Noto YI, Yagi Y, Inaba A, Abe K, Misawa S, Orimo S, Kobayashi T, Kamata T, Nakagawa M, Kuwabara S, Mizusawa H, Yokota T. Spreading of amyotrophic lateral sclerosis lesions--multifocal hits and local propagation? J Neurol Neurosurg Psychiatry 2014; 85(1): 85-91.

Shimazawa R, Ikeda M. Approval gap of pharmacogenomic biomarkers and in vitro companion diagnostics between the United States and Japan. J Clin Pharm Ther 2014; 39: 210-214.

Shirai T, Saito M, Kobayashi A, Asano M, Hizume M, Ikeda S, Teruya K, Morita M, Kitamoto T. Evaluating prion models based on comprehensive mutation data of mouse PrP. Structure 2014; 22(4): 560-571.

Takenouchi T, Ohyagi M, Torii C, Kosaki R, Takahashi T, Kosaki K. Porencephaly in a fetus and HANAC in her father: Variable expression of COL4A1 mutation. Am J Med Genet A 2014; doi: 10.1002/ajmg.a.36823. [Epub ahead of print]

Takigawa M, Takahashi A, Kuwahara T, Takahashi Y, Okubo K, Nakashima E, Watari Y, Nakajima J, Takagi K, Yamao K, Fujino T, Sugiyama T, Kimura S, Hikita H, Irioka T, Hirao K, Isobe M. Late-Phase Thromboembolisms after Catheter Ablation for Paroxysmal Atrial Fibrillation. Circulation J 2014; 78: 2394-2401.

Tanaka N, Nanri K, Taguchi T, Tanaka N, Fujita T, Mitoma H, Kawata A, Mizusawa H. The utility of voxel-based morphometry in the diagnosis of spinocerebellar degeneration. Brain Nerve 2014; 66(6): 699-704.

Titulaer MJ, Höftberger R, Iizuka T, Leypoldt F, McCracken L, Cellucci T, Benson LA, Shu H, Irioka T, Hirano M, Singh G, Calvo AC, Kaida K, Morales PS, Wirtz PW, Yamamoto T, Reindl M, Rosenfeld MR, Graus F, Saiz A, Dalmau J. Overlapping demyelinating syndromes and anti-NMDA receptor encephalitis. Ann Neurol 2014; 75: 411-428.

Yagi Y, Yokote H, Watanabe Y, Amino T, Kamata T, Kusunoki S. Taste impairment in Miller Fisher syndrome. Neurol Sci 2014 Aug 13 [Epub ahead of print]

Yamashita C, Tomiyama H, Funayama M, Inamizu S, Ando M, Li Y, Yoshino H, Araki T, Ichikawa T, Ehara Y, Ishikawa K, Mizusawa H, Hattori N. The evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease. Neurobiol aging 2014; 35(7): 1779.e17-21.

Yasui K, Yabe I, Yoshida K, Kanai K, Arai K, Ito M, Onodera O, Koyano S, Isozaki E, Sawai S, Adachi Y, Sasaki H, Kuwabara S, Hattori T, Sobue G, Mizusawa H, Tsuji S, Nishizawa M, Nakashima K. A 3-year cohort study of the natural history of spinocerebellar ataxia type 6 in Japan. Orphanet J Rare Dis 2014; 9(1): 118.

Yokote H, Nose Y, Ishibashi S, Tanaka K, Takahashi T, Fujihara K, Yokota T, Mizusawa H. Spinal cord ring enhancement in patients with neuromyelitis optica. Acta Neurol Scand 2015 Jan 7. doi: 10.1111/ane.12354. [Epub ahead of print]

Zeniya S, Yuno A, Watanabe T, Usui T, Moriki Y, Uno Y, Miake H. A 22-year-old Woman with Hypocalcemia and Clinical Features of Albright Hereditary Osteodystrophy Diagnosed with Sporadic Pseudohypoparathyroidism Type Ib Using a Methylation-specific Multiplex Ligation-dependent Probe Amplification Assay. Intern Med 2014; 53(9): 979-986.

渡邊耕介,吉岡耕太郎,日詰正樹,金澤俊郎,田中宏明.妊娠中に中耳炎を生じ産褥期にseptic dural sinus thrombosis に至った1 例.脳卒中 2014; 36(5): 356-360.

榊原 聡子, 饗場 郁子, 齋藤 由扶子, 犬飼 晃, 石川 欽也, 水澤 英洋.Spinocerebellar ataxia type 31(SCA31)の臨床像,画像所見―Spinocerebellar ataxia type 6(SCA6)との小脳外症候の比較検討―臨床神経学 2014; 54(6): 473-479

Hashimoto Y, Honda T, Matsumura K, Nakao M, Soga K, Katano K, Yokota T, Mizusawa H, Nagao S, Ishikawa K. Quantitative Evaluation of Human Cerebellum-Dependent Motor Learning through Prism Adaptation of Hand-Reaching Movement. PLoS One 2015 Mar 18;10(3):e0119376. doi: 10.1371/journal.pone.0119376. eCollection 2015.

Hattori T, Arai A, Yokota T, Imadome K, Tomimitsu H, Miura O, Mizusawa H. Immune-mediated Neuropathy with Epstein-Barr virus-positive T-cell Lymphoproliferative Disease. Intern Med 2015;54(1):69-73. doi: 10.2169/internalmedicine.54.3173. Epub 2015 Jan 1.

Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T. Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45-55 with a cocktail of vivo-morpholinos in mdx52 mice. Mol Ther Nucleic Acids 2015 Feb 3;4:e225. doi: 10.1038/mtna.2014.76.

Iwata R, Nakayama F, Hirochi S, Sato K, Piao W, Nishina K, Yokota T, Wada T. Synthesis and properties of vitamin E analog-conjugated neomycin for delivery of RNAi drugs to liver cells. Bioorg Med Chem Lett 2015 Feb 15;25(4):815-9. doi: 10.1016/j.bmcl.2014.12.079. Epub 2015 Jan 6.

Akaza M, Tanaka K, Tanaka M, Sekiguchi T, Misawa T, Nishina K, Kawachi I, Nishizawa M, Mizusawa H, Yokota T. Can anti-AQP4 antibody damage the blood-brain barrier? Eur Neurol 2014;72(5-6):273-7. doi: 10.1159/000360619. Epub 2014 Oct 14.

Ozaki K, Irioka T, Ishikawa K, Mizusawa H. CADASIL with a Novel NOTCH3 Mutation (Cys478Tyr). J Stroke Cerebrovasc Dis 2015 Mar;24(3):e61-2. doi: 10.1016/j.jstrokecerebrovasdis.2014.11.022. Epub 2015 Jan 13.

Obayashi M, Stevanin G, Synofzik M, Monin ML, Duyckaerts C, Sato N, Streichenberger N, Vighetto A, Desestret V, Tesson C, Wichmann HE, Illig T, Huttenlocher J, Kita Y, Izumi Y, Mizusawa H, Schöls L, Klopstock T, Brice A, Ishikawa K, Dürr A. Spinocerebellar ataxia type 36 exists in diverse populations and can be caused by a short hexanucleotide GGCCTG repeat expansion. J Neurol Neurosurg Psychiatry 2014 Dec 4. pii: jnnp-2014-309153. doi: 10.1136/jnnp-2014-309153.

総説・著書
古川迪子, 水澤英洋. 認知機能障害を呈する中枢神経感染症. 日本臨牀: 72(4), 734-747 (2014).

三條伸夫, 馬嶋貴正, 能勢裕里江. 神経細胞の動態. 多発性硬化症のパラダイムシフト ―病態から治療まで― . Clinical Neuroscience: 32, 1232-1235 (2014).

三條伸夫. プリオン病. 神経内科疾患の診療. 2015. 神経内科研修ノート(初版) : 372-375.

三條伸夫, 水澤英洋. プリオン病. 付録2. 感染症関連ガイドラインと使用上の注意. 2014. アクチュアル脳・神経疾患の臨床 神経感染症を究める(第1版): 352-354.

三條伸夫, 水澤英洋. プリオン病. 2014. アクチュアル脳・神経疾患の臨床 神経感染症を究める(第1版): 278-285.

石田和之. Sleep-Related Leg Crampに対する牛車腎気丸の有効性: 有効症例の東洋医学的特徴についての検討. 日本東洋医学雑誌: 65, 100-107 (2014).

冨滿弘之.疫学調査とその基礎となる診断基準. 炎症と免疫: 22, 185-189 (2014).

沼沢祥行,川越正平,水澤英洋.Duloxetineが多系統萎縮症の嚥下障害に対して一定の効果がある可能性. 神経内科: 80(5), 617 (2014).

石田和之, 村松慎一. 神経内科に役立つ漢方薬:認知症とパーキンソン病の漢方治療を中心に. 難病と在宅ケア: 20, 33-37 (2014).

Shimazawa R, Ikeda M. Conflicts of interest in psychiatry: strategies to cultivate literacy in daily practice. Psychiatry Clin Neurosci. 68: 489-497, 2014.

三浦義治, 水澤英洋. 進行性多巣性白質脳症. 2014. 別冊 最新医学 新しい診断と治療のABC 神経関連感染症: 182-191.

三浦義治, 味澤篤. 進行性多巣性白質脳症. 2014. 長期療養時代のHIV感染症/AIDSマニュアル: 209-214.

三浦義治. HIV感染症. 2014. アクチュアル脳・神経疾患の臨床 神経感染症を究める(第1版): 121-128.

三浦義治. HIV感染症 付録2. 感染症関連ガイドラインと使用上の注意. 2014. アクチュアル脳・神経疾患の臨床 神経感染症を究める(第1版): 345-348.

三浦義治. HIV-1関連脊髄症. 2014. 別冊日本臨牀 新領域別症候群シリーズ 神経症候群(第2版) Ⅴ: 149-152.

沼沢祥行,水澤英洋.医薬品副作用,中毒性疾患 医薬品による神経・筋骨格系障害概論. 2014. 別冊日本臨牀 新領域別症候群シリーズ 神経症候群(第2版) Ⅴ: 539-544.


認知生物学分野

原著
K Shoi, K Fueki, N Usui, M Taira, N Wakabayashi. Influence of posterior dental arch length on brain activity during chewing in patients with mandibular distal extension removable partial dentures. J Oral Rehabil. 41(7):486-95, 2014. doi: 10.1111/joor.12169.

Kawakubo N, Miyamoto JJ, Katsuyama N, Ono T, Honda E, Kurabayashi T, Taira M, Moroyama K. Effects of cortical activations on enhancement of handgrip force during teeth clenching: An fMRI study. Neurosci Res. 79:67-75, 2014. doi: 10.1016/j.neures.2013.11.006.

脳神経機能外科分野

原著

Choi SH*, Tamura K*, Khajuria RK, Bhere D, Nesterenko I, Lawler J, Shah K: Antiangiogenic Variant of TSP-1 Targets Tumor Cells in Glioblastomas. Mol Ther, 23(2):235-43, 2015 * equal contribution

Duebgen M, Martinez-Quintanilla J, Tamura K, Hingtgen S, Redjal N, Wakimoto H, Shah K: Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy. J Natl Cancer Inst 106:dju090, 2014

Hayashi S, Maehara T, Mukawa M, Aoyagi M, Yoshino Y, Nemoto S, Ono T, Ohno K: Successful coil embolization of a ruptured basilar artery aneurysm in a child with leukemia: a case report. Neurol Med Chir (Tokyo) 54:150-154, 2014

Hirose Y, Hara K, Miyajima M, Matsuda A, Maehara T, Hara M, Matsushima E, Ohta K, Matsuura M: Changes in the duration and frequency of deviant stimuli engender different mismatch negativity patterns in temporal lobe epilepsy. Epilepsy Behav 31:136-142, 2014

Hiura M, Nariai T, Ishii K, Sakata M, Oda K, Toyohara J, Ishiwata K: Changes in cerebral blood flow during steady-state cycling exercise: a study using oxygen-15-labeled water with PET. J Cereb Blood Flow Metab 34:389-396, 2014

Ishii Y, Nariai T, Tanaka Y, Mukawa M, Inaji M, Maehara T, Ohno K: Practical clinical use of dynamic susceptibility contrast magnetic resonance imaging for the surgical treatment of moyamoya disease. Neurosurgery 74:302-309, 2014

Kawano Y, Maehara T, Ohno K: Validation and evaluation of the volumetric measurement of cerebellopontine angle cistern as a prognostic factor of microvascular decompression for primary trigeminal neuralgia. Acta Neurochir (Wien) 156:1173-1179, 2014
Kishikawa M, Tsunoda A, Tanaka Y, Kishimoto S: Large nasopharyngeal inverted papilloma presenting with rustling tinnitus. Am J Otolaryngol 35:402-404, 2014

Kiyokawa J, Yamaguchi K, Okada R, Maehara T, Akita K: Origin, course and distribution of the nerves to the posterosuperior wall of the external acoustic meatus. Anat Sci Int 89:238-245, 2014

Majd.N, Sumita K, Yoshino H, Chen D, Terakawa J, Daikoku T, Kofuji S, Curry R, Wise-Draper T, Warnick R, Guarnascheli J, Sasaki A: A review of the Potential Utility of Mycophenolate Mofetil as a Cancer Therapeutic. Journal of Cancer Resarch, 423401, 2014

Momose T, Nariai T, Kawabe T, Inaji M, Tanaka Y, Watanabe S, Maehara T, Oda K, Ishii K, Ishiwata K, Yamamoto M: Clinical benefit of 11C methionine PET imaging as a planning modality for radiosurgery of previously irradiated recurrent brain metastases. Clin Nucl Med 39:939-943, 2014

Sugawara T, Maehara T, Tadashi N, Aoyagi M, Ohno K: Independent predictors of shunt-dependent normal pressure hydrocephalus after aneurysmal subarachnoid hemorrhage. J Neurosurg Sci, 2014

Sugawara T, Aoyagi M, Ogishima T, Kawano Y, Tamaki M, Yano T, Tsunoda A, Ohno K, Maehara T, Kishimoto S: Extended Orbital Exenteration for Sinonasal Malignancy with Orbital Apex Extension-Surgical Technique and Clinical Analysis-. J Neurosurg Mar 27:1-7, 2015 [Epub ahead of print]

Tamura K, Aoyagi M: CD133-positive stem cells. Response. J Neurosurg 120:1012, 2014

Tamura K, Aoyagi M: Stem cells and the origin of different glioma subtypes. Response. J Neurosurg 120:1010-1011, 2014

Yamada M, Tsunoda A, Tokumaru T, Aoyagi M, Kawano Y, Yano T, Kishimoto S: Surgery for juvenile nasopharyngeal angiofibroma with lateral extension to the infratemporal fossa. Auris Nasus Larynx 41:359-363, 2014

Yamamoto M, Kawabe T, Higuchi Y, Sato Y, Nariai T, Watanabe S, Barfod BE, Kasuya H: Validity of Prognostic Grading Indices for Brain Metastasis Patients Undergoing Repeat Radiosurgery. World Neurosurg 82:1242-1249, 2014

Zhang X, Tong F, Li CX, Yan Y, Nair G, Nagaoka T, Tanaka Y, Zola S, Howell L: A fast multiparameter MRI approach for acute stroke assessment on a 3T clinical scanner: preliminary results in a non-human primate model with transient ischemic occlusion. Quant Imaging Med Surg 4:112-122, 2014

総説・著書

Nariai T, Inaji M, Sakata M, Toyohara J: Use of (11)C-4DST-PET for Imaging Human Brain Tumors., in Hayat M (ed): Tumors of the central nervous system. Amsterdam: Springer, Vol 11, pp 41-48, 2014

稲次基希、大野喜久郎:III細菌感染症 脳膿瘍、硬膜下膿瘍、硬膜外膿瘍. アクチュアル 脳・神経疾患の臨床 神経感染症を極める. 辻 省次総編集、水澤英洋専門編集. 東京: 中山書店. P151-157, 2014

稲次基希、前原健寿. てんかんの診断 PET,SPECT,MEG 日本臨床 72(5):827-833, 2014

稲次基希、前原健寿. てんかん てんかんであることをどう見極める?鑑別は? 特集 神経診察―そのポイントと次の一手 各論. Medicina 51(7):1294-99, 2014

成相 直. 間接的血行再建術を用いたもやもや病の治療 小児の脳神経 38:388-394, 2013

成相 直. グリオーマの診断と治療に有効な放射線診断学の進歩 脳神経外科ジャーナル 23:559-568, 2014

田中洋次, 成相 直, 前原健寿. 脳神経外科領域における3D ASL撮影の有用性. GE today 45:12-15, 2014