`Curriculum Vitae`
Department of Stem Cell Biology, Medical Research Institute, Tokyo Medical and Dental University Japan
Division of Aging and Regeneration, The Institute of Medical Science, The University of Tokyo
Emi K. Nishimura, M.D., Ph.D
Education:
1996-2000 :@@Ph.D.  Kyoto University Graduate School of Medicine
1988-1994 :@@M. D.  Shiga University of Medical Science


Professional Training and Experience
2021- : Professor, Division of Aging and Regeneration, The Institute of Medical Science, The University of Tokyo
2009-present : Professor, Department of Stem Cell Biology, Medical Research Institute,
Tokyo Medical and Dental University
2006 : Professor, Cancer Research Institute, KanazawaUniversity
2004 : Associate Professor, Creative Research Institute gSouseih (CRIS),
Hokkaido University
2001: SPS Postdoctoral Fellow for Research Abroad, Harvard medical School
2000 : Research Fellow, Dana-Farber Cancer Institute, Harvard Medical School
2000 : Received Ph.D. from Kyoto University
1994 : Resident, Department of Dermatology, Kurashiki Hospital
1994 : Graduated from Shiga University of Medical Science


Awards:
2017: Myron Gordon Award International Federation of Pigment Cell Societies(IFPCS)
2013: The 2013Rsearch Achievement Award@ American Skin Associations
2012: The 8th Japan Academy Medal Prize The Japan Academy
2012: Ogawa-Seiji Award Lydia O'Leary Memorial Foundation
2012: Eighth JSPS PRIZE Award Japan Society for the Promotion of Science
2007: The Young Scientists' Prize Ministry of Education, Culture, Sports,ScienceandTechnology-Japan
2003: Minami Memorial Award
(52nd Japanese Dermatological Association Award)
Charles A. King Trust Postdoctoral Research Fellowship
Japanese Dermatological Association
2002: Shiseido Award Shiseido Company, Limited


Society membership:

Japanese Society for Investigative Dermatology

International Society for Stem Cell Research

Japanese Society for Pigment Cell Research

Japanese Association for Cancer Research

Japanese Dermatological Association

Molecular Biology Society of Japan





`Biodata (Biographic Profile)`
Emi K. Nishimura, M.D., Ph.D
Dr. Emi Nishimura obtained her MD in 1994 and did her dermatology residency in Kyoto University Hospital.
She then obtained her PhD in Shin-Ichi Nishikawa's lab at Kyoto University, studying melanocyte development, where she subsequently identified melanocyte stem cells.Dr. Nishimura did her post-doc training in David Fisher's lab in the Dana Farber Cancer Institute, Harvard Medical School, and extended her melanocyte stem cell research there. She then started her own group as an Associate Professor at Hokkaido University, subsequently becoming Professor at Kanazawa University the following year.Her lab then moved to Tokyo Medical and Dental University in 2009. She is currently a Professor in the Department of Stem Cell Biology within the Medical Research Institute of Tokyo Medical and Dental University.


Selected publication:
  1.  Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y, Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK.
Obesity accelerates hair thinning by stem cell-centric converging mechanisms.
Nature, 595:266-271, 2021
  2.  Kato T, Liu N, Morinaga H, Asakawa K, Muraguchi T, Muroyama Y, Shimokawa M, Matsumura H, Nishimori Y, Tan LJ, Hayano M, Sinclair DA, Mohri Y, Nishimura EK.
Dynamic stem cell selection safeguards the genomic integrity of the epidermis.
Developmental Cell, 56,3309-3320,
2021
3. Matsumura H, Liu N, Nanba D, Ichinose S, Takada A, Kurata S, Morinaga H, Mohri Y, De Arcangelis A, Ohno S, Nishimura EK
Distinct types of stem cell divisions determine organ regeneration and aging in hair follicles.
Nature Aging, 1:190-204, 2021
4. Liu N, Matsumura H, Kato T, Ichinose S, Takada A, Namiki T, Asakawa K, Morinaga H, Mohri Y, De Arcangelis, Geroges-Labousse E, Nanba D, Nishimura EK. :Stem cell competition orchestrates skin homeostasis and ageing.
Nature, 568(7752):344-350,
2019
5. Matsumura H, Mohri Y, Binh NT, Morinaga H, Fukuda M, Ito M, Kurata S, Hoeijmakers J, Nishimura EK.: Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis.
Science, 351(6273):535, 2016

6. Okamoto N, Aoto T, Uhara H, Yamazaki S, Akutsu H, Umezawa A, Nakauchi H, Miyachi Y, Saida T, Nishimura EK.
A melanocyte-melanoma precursor niche in sweat glands of volar skin.
Pigment Cell & Melanoma Research, 27(6):1039-1050, 2014
7. Ueno M, Aoto T, Mohri Y, Yokozeki H, Nishimura EK.
Coupling of the radiosensitivity of melanocyte stem cells to their dormancy a hair cycle.
Pigment Cell & Melanoma Research, 27(4):540-551,
2014
8. Nishimura EK. Melanocyte stem cells: A melanocyte reservoir in hair follicles for hair and skin pigmentation.
Pigment Cell Melanoma Res., 24(3): 401-410, 2011
9. Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, Nakauchi H, Tanaka Y,  McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK.
Hair follicle stem cells provide a functional niche for melanocyte stem cells. Cell Stem Cell, 8, 177-187, 2011
10. Nishimura EK., Suzuki M, Igras V, Du J, Lonning S, Miyachi Y, Roes J, Beerman F, Fisher DE.
Key Roles for Transforming Growth Factor ƒΐ in Melanocyte Stem Cell Maintenance  Cell Stem Cell, 6(2):130-140, 2010
11. Inomata K, Aoto T, Binh NT, Okamoto N, Tanimura S, Wakayama T, Iseki S, Hara E, Masunaga T, Shimizu H, Nishimura EK.
Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation. Cell, 137(6):1088-99, 2009
12. Nishimura, E.K, Granter, S.R., Fisher, D.E. Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche Science, 307(5710):720-724. 2005
13. Nishimura, E.K., Jordan, S.A, Oshima, H., Yoshida, H., Osawa, M., Jackson, I.J., Barrandon, Y., Yoshiki, M. Nishikawa, SI.
Dominant Role of the Niche in Melanocyte Stem Cell Fate Determination. Nature, 416(6883):854-60, 2002.